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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYNucleosomesNucsare the repeating units of chromatinmade up of DNA wrapped around a histone octamerChanges in chromatin structurefunction can dramatically impact downstream gene expression and cellular physiologydriving oncogenic reprogramming and cancer progressionThis epigenetic regulation of chromatin is controlled by two major modificationshistone post translational modifications ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Adolescent Real World Simulation e-Learning Program

    SBC: INDEPENDENT LIVING RESOURCES, INC.            Topic: NIMHD

    DESCRIPTION (provided by applicant): The purpose of the proposed project is to develop, implement, and evaluate the use of an Internet-based eLearning multimedia program that will allow foster care social workers, educators, and other youth workers to planone-day real world simulations that would allow adolescent foster youths, ages 13-21, to learn and practice independent living skills. Research ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Indoor Navigation Aid for Blind and Visually-Impaired Individuals in Unfamiliar Spaces

    SBC: VORTANT TECHNOLOGIES, LLC            Topic: N

    Project Summary Abstract Confusionbeing lostand losing track of oneandapos s orientation within large or unfamiliar indoor spacesthese are some of the biggest challenges facing people with visual disabilitiesSince GPS typically doesnandapos t work indoorsand isnandapos t fine grained enough anywayindividuals who cannot readily access visual information are at a significant disadvantageand many bli ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A Low-Cost Platform for Routine High-Accuracy Sizing of Nucleic Acid Samples with 100 bp- 100 Mbp Dynamic Range

    SBC: Genturi Inc.            Topic: 172

    The goal of this project is to develop a microand nanofluidic DNA sizing platform with a sensitivityspeedand dynamic range that is unmatched by current sizing technologiesWe find that fluorescence burst analysis of individual DNA molecules transported through sub micrometer scale channels provides accurate and precise sizing of fragments betweenbp ands of MbpIn this singlemolecule sizing platformu ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Nanotechnology Enabled Diagnostic Platform for Early Stage Cancer Detection

    SBC: Inanovate, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this proposal is the development, evaluation and validation of an accurate, low cost diagnostic test that can discriminate prostate cancer from benign prostatic hyperplasia to a Specificity of 85% at aSensitivity of 85%. Prostate cancer is the most common cancer in men, with a probability of 1 in 6. Approximately 29% of all cancer cases in ma ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  7. An Integrative Approach to Control Group Creation for Prevention Research

    SBC: Prevention Strategies, LLC            Topic: 550

    PROJECT ABSTRACTThe goal of this Phase II SBIR project is to develop a method for creating algorithmically generated control groupsvirtual controlsThese will be composed of synthetic cases that have two characteristicspretest similarity to whatever prevention treatment group may present itself andpatterns of change over time that closely mimic the normal course of alcohol and drug use developmentT ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A novel class of anti-acne therapeutics

    SBC: Verge Therapeutics            Topic: NIAMS

    Acne Vulgaris is a common skin disorder that affectsof the populationtypically teenagers and young adultsOvermillion people in the US are affected by acne generating a $billion market for acne treatmentsof which is derived from prescription medicationsAlthough acne is not a life threatening conditionit still has a high psychosocial impact resulting in depressionanxietyangersuicidal thoughtsphysica ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation

    SBC: Deep Blue Medical Advances, Inc.            Topic: 300

    Two million laparotomies are performed annually in the U Swith ventral hernia being a frequent complication inof patients and costing as much as $billion annuallyThe ten year ventral hernia recurrence rate is reportedlywithout hernia mesh andwhen a mesh is added to the repair and these numbers underestimate recurrence rates in the rapidly growing morbidly obese population in the USIn Junein the La ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
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