Award Data

Creare is developing a miniature power system for NOA weather monitoring stations in remote locations. This system can provide electric power continuously from naturally occurring temperature differences that exist between ambient air and water in environments such as the Arctic Ocean and the Great Lakes. Generating power directly from these temperature difference uses the atmosphere and ocean/lat ...

This Phase II effort prototypes a minimal volume microscope designed to allow for a 2-D digital holographic imaging concurrent with field of view spectral content at video frame rates. The use of a laser driven IR dual beam frequency comb, coincident with the optical beam path required for a digital holographic image, will allow rapid acquisition of both the spatial and the spectral content associ ...

Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...