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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Novel Microfludic Device for Drug Toxicity Studies
SBC: CFD RESEARCH CORPORATION Topic: CBD10103Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture
SBC: Physical Optics Corporation Topic: CBD10103Poor drug candidates are often identified late in the drug development process (e.g., in the preclinical and clinical phases) and contribute significantly to the high cost and low yield of drug discovery. As a result, new tools are needed to accelerate the assessment of drug candidate toxicity earlier in the drug development process. To address this Chemical/Bio Defense (CBD) need, Physical Optics ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants
SBC: CFD RESEARCH CORPORATION Topic: CBD10107Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
MicroLens Hyperspectral Imager for Standoff Chemical Detection
SBC: SURFACE OPTICS CORP. Topic: CBD171002A program to develop a compact, MLA-based, LWIR, full-motion-video hyperspectral imager for chemical detection is proposed. The proposed Hyperspectral Chemical Imaging Sensor (HyCIS) builds upon Surface Optics’ real-time hyperspectral imaging activities, including our 3D full-motion-video spectral imaging (FMV-SI) technology and our MIDIS hyperspectral image processor. Simultaneously sampling 16 ...
SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense -
MicroLens Hyperspectral Imager for Standoff Chemical Detection
SBC: SA PHOTONICS, LLC Topic: CBD171002SA Photonics is please to submit the proposal for the HawkEye compact LWIR hyperspectral imaging system. HawkEye leverages SA Photonics previous visible, SWIR, and LWIR programs to result in a compact, hand held, battery operated hyperspectral imager in a low cost design approach. Furthermore, HawkEye will leverages SA Photonics expertise in warfighter body worn equipment and ground troop personal ...
SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense -
Miniature Residual Life Indicator
SBC: Physical Optics Corporation Topic: CBD10106To address the Chemical and Biological Defense (CBD) need for a residual life indicator (RLI) capable of determining the degradation in physical adsorption and reactive capacity arising from battlefield contaminants and exposure to the elements, Physical Optics Corporation (POC) proposes to continue the development of a new Miniature Residual Life Indicator (MRLIN). MRLIN is based on impedance spe ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device
SBC: Physical Optics Corporation Topic: CBD10102To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to advance development of a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses mature components ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
Next Generation Integrated Electrophoretic Nanofluidic Biochip Sensor Platform for the THz Spectroscopic Finger Printing of Biological Species and Age
SBC: REDONDO OPTICS, INC. Topic: CBD10110Redondo Optics Inc. (ROI), proposes to develop and demonstrate a next generation integrated electrophoretic nanofluidic biochip (INTRay-Nanochip) sensor platform for the"label-less"THz spectroscopy finger printing of biological species and agents. In the proposed Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
Photoacoustic Gasses Optical Detector and Analyzer
SBC: Physical Optics Corporation Topic: CBD171004To address the CBD’s need for real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA) autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In t ...
SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense -
Tomographic Nanoscopy for Pathogen Identification
SBC: SOLID STATE SCIENTIFIC CORPORATION Topic: CBD171003This Phase II effort prototypes a minimal volume microscope designed to allow for a 2-D digital holographic imaging concurrent with field of view spectral content at video frame rates. The use of a laser driven IR dual beam frequency comb, coincident with the optical beam path required for a digital holographic image, will allow rapid acquisition of both the spatial and the spectral content associ ...
SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense