Award Data

Currently, no commercial products exist for the repair of large injuries to muscle, particularly volumetric muscle loss (VML). In Phase I of this project, data demonstrated that keratin biomaterials can provide temporal release of growth factors while maintaining cell viability in vitro and in vivo. In Phase II, the biomaterial formulation was optimized for spatio-temporal delivery of cells and gr ...

The objective of this project is to develop, produce, and commercialize a liquid-tight, field-applicable, ocular patch for wound stabilization and treatment of the eye following a war-related injury to the ocular surface. The patch consists of a curved flexible silicone membrane (similar in size and shape to a contact lens) which has had (1) a novel bio-adhesive

Burn injuries, particularly those to the face, present a number of functional and psychological challenges that arise from scarring and related contracture. A major goal of trauma and burn surgeons is to prevent scarring and improve grafting technologies given the complexity of facial topography. This project seeks to optimize and finalize a prototype of a 3D printed keratin facemask capable of ...

The objective of the Phase II project is to develop a Residual Limb Health Monitoring Platform based on the Phase I findings and will integrate a sensor equipped smart socket liner, smart socket with radio transceiver and power source, and health monitoring software. Significantly, the software and hardware are open interface for new, 3rd party sensors, data transfer protocols, and prosthetic c ...

Elevated levels of human butyrylcholinesterase (hBuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of hBuChE in the plasma for days or weeks. Thus far, plasma-derived hBuChE and PEGylated recombinant forms of BuChE (rBuChE) have been tested in ...

Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. We demonstrated during Phase I of this project that we can design and fabricate hybrid closure systems which incorporate areas of microfiber adhesive arrays inspired by the foot-hairs found on geckos which ha ...

Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare proposes to develop a hermetic garment closure system that seals macroscopic and microscopic gaps at interfaces and closures and pro ...

Chemical, biological, or toxin attacks in military and civilian settings are a serious and growing concern. Standard first aid for exposure to some chemical warfare agents and toxins includes the immediate administration of relevant antidotes using an autoinjector. When an attack occurs, pre-filled autoinjectors must be immediately available and thus highly portable, and they must be suitable fo ...

Phase 2 involves the continued development of the F-MIRE FAES system. The FAES system insertion loss measurements utilize a sub-miniature MEMS microphone mounted in the ear canal of the HPD wearer. An ultra-thin flat flexible cable connects the microphone to a signal conditioning unit and power supply. The microphone is mounted in a foam ear dam to protect the microphone and the sensitive ear ...

Under a Phase II program, DRS Scientific will build, test, and deliver a new type of Acousto-Optic Tuned Filter (AOTF) hyperspectral imager that is compact, rugged, and inexpensive, has no moving parts, and is fast and sensitive. It will cover 8-12 micron wavelength range with 10 wavenumber spectral resolution or finer, and will have micro-Flick sensitivity with a cooled camera, and