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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.

    SBC: Qrono, Inc.            Topic: CBD13107

    Elevated levels of human butyrylcholinesterase (hBuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of hBuChE in the plasma for days or weeks. Thus far, plasma-derived hBuChE and PEGylated recombinant forms of BuChE (rBuChE) have been tested in ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments

    SBC: NANOGRIPTECH            Topic: CBD13109

    Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. We demonstrated during Phase I of this project that we can design and fabricate hybrid closure systems which incorporate areas of microfiber adhesive arrays inspired by the foot-hairs found on geckos which ha ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  3. Hermetic Seals for Chemical/Biological Protective Garments

    SBC: CREARE LLC            Topic: CBD13109

    Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare proposes to develop a hermetic garment closure system that seals macroscopic and microscopic gaps at interfaces and closures and pro ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  4. A Miniature Autoinjector for Multicomponent Drugs and Vaccines

    SBC: CREARE LLC            Topic: CBD13106

    Chemical, biological, or toxin attacks in military and civilian settings are a serious and growing concern. Standard first aid for exposure to some chemical warfare agents and toxins includes the immediate administration of relevant antidotes using an autoinjector. When an attack occurs, pre-filled autoinjectors must be immediately available and thus highly portable, and they must be suitable fo ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  5. Decontamination Assurance Spray

    SBC: AGENTASE LLC            Topic: CBD05103

    There are many products that can identify chemical weapons. They range in complexity from simple colorimetric chemical test strips or gas tubes, to more complex multi-step test kits, to intricate arrays of gas chromatographs and mass spectrometers. None of the products is specifically designed to illustrate the presence of chemicals on surfaces or have use as a decontamination assurance method. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  6. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  7. Novel THz-frequency spectrometers by integrating widely-tunable monochromatic THz sources and detectors, or arrays of emitters and detectors, with pho

    SBC: ArkLight            Topic: CBD04104

    By continuing teaming up with one of the most reputable university teams in THz science and technology, ArkLight proposes to carry out the tasks set for a Phase-II program following our success in Phase I. We are aimed at the further development of novel spectrometers to analyze chemicals in the vapor phase based on accurate measurements of the emission and absorption spectra due to the molecular ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Model-Based Design of Test Systems for Chemical Protective Clothing

    SBC: CREARE LLC            Topic: CBD02202

    The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. In Silico Screening for Biothreat Countermeasures

    SBC: QUANTUMBIO INC            Topic: CBD05106

    The current state of the art of in silico drug discovery or computer aided drug discovery relies almost exclusively on molecular mechanics force fields, such as AMBER and CHARMM, and empirical potentials. It is well known that while these approaches are excellent for certain applications, they have thus far proven less then satisfactory for thorough understanding the interactions of enzyme-inhibi ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
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