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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYNucleosomesNucsare the repeating units of chromatinmade up of DNA wrapped around a histone octamerChanges in chromatin structurefunction can dramatically impact downstream gene expression and cellular physiologydriving oncogenic reprogramming and cancer progressionThis epigenetic regulation of chromatin is controlled by two major modificationshistone post translational modifications ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A cell-free, high-throughput screening service for accelerated GPCR ligand discovery

    SBC: KXT BIO INC.            Topic: 300

    PROJECT SUMMARY The proposed Phase I STTR project is a partnership between a biotechnology company KXTbioIncand the University of North Carolina at Chapel Hill to develop an innovative high throughput screening service for identifying new drug candidates that act via G protein coupled receptorsGPCRsThis large protein superfamily has been the most successful source of therapeutic targetsaccounting ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular Dystrophies

    SBC: BAEBIES, INC.            Topic: NICHD

    ABSTRACT A Comprehensive Newborn Screening Solution for Duchenne and Congenital Muscular DystrophiesFast Track SBIRCongenital genetic abnormalities are a leading cause of childhood mortality and morbidityWhile routine newborn screeningNBShas dramatically improved health outcomesmany congenital disorders such as Duchenne muscular dystrophyDMDand other congenital muscular dystrophiesCMDare not curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. ACTIVESTOP DYNAMIC WRIST PROTECTOR FOR SPORTS

    SBC: Simbex LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is to research the technical and commercial feasibility of a novel wrist brace that reduces the risk for wrist fracture by resisting wrist terminal extension while otherwise allowing unconstrained movement throughout the normal range of motion. The novel wrist brace will be designed, fabricated, and validated in our laboratory und ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA

    SBC: THREE C INSTITUTE FOR SOCIAL DEVELOPMT            Topic: N/A

    Location 1903 N HARRISON AVE, STE 101 CARY, NC 27513 United States N44MH0664102C $365 147.00 2 005 ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA Department of Health and Human Services National Institutes of Health SBIR PHS2006-1 THREE C INSTIT ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Adaptive Web-based Software for Enhancing Social Communication Skills in Youth with Autism Spectrum Disorder to Facilitate Employment Success

    SBC: 3-C Institute for Social Development, Inc.            Topic: NIDCD

    Abstract Autism Spectrum DisorderASDis a life long neurodevelopmental disorder characterized by social communication deficits and repetitive behaviors and interestsWith overyouth with ASD entering adulthood in the next decadethere is an urgent need for the development of cost effectiveaccessibleand evidence based interventions to support the transition to competitive employmentLike their typically ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A Device for Stereotype Quantification

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Stereotypy, describing motor behavior that is repetitive, rhythmical, and non-goal directed, is commonly observed in persons with autism and other developmental disabilities. For some children with autism or other developmental disabilities, stereotypy may be a target for intervention. On the other hand, stereotypy may serve as a proxy for other behaviors or co ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Adipose Derived Adult Stem Cells in Hepatic Regeneration

    SBC: VESTA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Liver failure secondary to hepatitis, hepatotoxin exposure, and cirrhosis threatens the lives of thousands in the United States alone. Estimates of yearly direct healthcare costs for liver disease in the U.S. range from $60 billion to over $100 billion. Vesta Therapeutics has developed proprietary technologies for the isolation and preservation of primary hepat ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Administrative Supplement for the Evaluation of the novel, uni-directional, Pd-103 CivaSheet for Lung Cancer

    SBC: CIVATECH ONCOLOGY INC            Topic: NCI

    Parent Award: R44CA217587 Clinical Evaluation of the novel, Uni-directional Pd-103 CivaSheet for Lung Cancers CivaTech Oncology’s mission is to provide improved radiation therapy directly to localized tumors. The Company has developed a novel, polymer-encapsulated, membrane-like radiation source that emits radiation on only one side of the device – CivaSheet®. This directional source is compa ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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