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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bronchopulmonary Dysplasia Drug Therapy

    SBC: Syntrix Biosystems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Bronchopulmonary dysplasia (BPD) is a disease affecting infants who become oxygen dependent as a result of prolonged mechanical ventilation with supplemental oxygen early in life. Barotrauma and elevated levels of oxygen induce direct injury to the immature lung tissue, resulting in an inflammatory response and infiltration by circulating neutrophils. When neu ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Doppler Ultrasound Automatic Mapping of Basal Cerebral Blood Flow

    SBC: SPENCER TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is to develop new Doppler ultrasound technology for automatic diagnostic mapping of blood flow in the basal arteries of the brain. These vessels include the middle cerebral artery, the anterior cerebral artery, and the posterior communicating artery. This technology will enable transcranial Doppler diagnostic workup of the acute stroke patient ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Synthesis and Evaluation of a Novel Anti-HIV Agent

    SBC: Kucera Pharmaceutical Company            Topic: N/A

    The long-term goal of this research is to develop a drug that is safe and effective against drug-resistant human immunodeficiency virus (HIV) infection. Several challenges confront current anti-HIV chemotherapy. The frequency of drug-resistant and multidrug-resistant HIV-1 is increasing. Toxicities associated with current HIV medications often result in the discontinuation of these therapies. Phys ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Internet-based Coping Skills Workbook for PTSD

    SBC: TALARIA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Exposure to trauma is common in the US. A significant proportion of these exposures leads to serious impairment in functioning, including posttraumatic stress disorder (PTSD). Although there are empirically-supported treatments (EST's) for PTSD, many individuals do not get the treatment they need. This grant proposes to use the Internet to deliver a coping skil ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. ENHANCING PEPTIDE DELIVERY TO THE BRAIN

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is the leading cause of death and disability in the US with an incidence rate of 1.5 million at cost of $56.3 billion annually. There is no treatment for TBI, and the lack of therapeutic intervention for a public health issue of this magnitude constitutes a healthcare crisis. We have developed COG133, a peptide that is neuroprotecti ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Crossroads: Cooperative High School Drug Prevention

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Adolescent drug use continues to be a major public health problem. The need for late onset drug prevention and early cessation in high schools is great, yet few universal programs exist that target alcohol, tobacco, and other drug use among high school students. Crossroads is a universal drug prevention program based on a cooperative relationship between high s ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Crossroads: Cooperative High School Drug Prevention

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Adolescent drug use continues to be a major public health problem. The need for late onset drug prevention and early cessation in high schools is great, yet few universal programs exist that target alcohol, tobacco, and other drug use among high school students. Crossroads is a universal drug prevention program based on a cooperative relationship between high s ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Educational Opportunities for Youth in Foster Care

    SBC: INDEPENDENT LIVING RESOURCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this project is to produce, test, and evaluate the use of a multimedia program for foster youths and adults who care for them. The program will connect foster and group home residents (youths), foster and group home parents, other caregivers, and youth serving professionals with information and resources to make post secondary educational opportu ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Commercialization of Human Visceral Adipocytes

    SBC: Zen-Bio, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The US is experiencing an epidemic rise in obesity and related co-morbidities such as type II diabetes. Epidemiological studies demonstrate that these co-morbidities are specifically correlated with visceral (intra-abdominal) fat deposition. To elucidate this association, a fully characterized and performance tested cultured human adipocyte cell system must be ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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