Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A NEW CLASS OF BIOSENSORS BASED ON THE USE OF COLLOIDAL GOLD DIRECTLY OR DEPOSITED AS A POROUS GOLD FILM. THE KEY TO THE APPROACH ISTHE IMMOBILIZATION OF ENZYMES ON GOLD SURFACES THAT PROVIDE FOR HIGHFLUX, HETEROGENEOUS ELECTRON TRANSFER. THE FEASIBILITY OF CONSTRUCTING THIS NEW CLASS OF BIOSENSORS WILL BE EVALUATED BY THE END OF PHASE I. THE OBJECTIVES ...

75655S The photovoltaics (PV) industry is having difficulty finding enough raw materials to match its rapid growth. In addition, traditional sources of secondary grade polysilicon are no longer readily available at inexpensive prices. Reducing the cost of solar silicon wafers is the key to lowering the price of crystalline silicon solar cells. This project will develop a single-step wafer fabr ...

CRYOGENIC HELIUM REFRIGERATORS AND LIQUIFIERS CONVENTIONALLYEMPLOY OIL LUBRICATED POSITIVE DISPLACEMENT COMPRESSORS AT THE WARM END AND FREQUENTLY USE PISTON TYPE EXPANSION ENGINES AT THE COLD END. THESE SYSTEMS REQUIRE EXTENSIVE AND VIGILANT MAINTENANCE TO CONTROL CONTAMINATION FROM LUBRICATING OIL AND ITS VOLATILE COMPONENTS MIGRATING TO THE COLD END. HENCE THE NEED FOR LOW MAINTENANCE COMPRESSO ...

IN MOST CRYOGENIC SYSTEMS, THE PIPING JOINTS IN COLD REGIONSOF THE SYSTEM ARE MADE BY WELDING OR SOLDERING. THIS IS ESSENTIAL BECAUSE EXISTING DESIGNS OF CRYOGENIC PIPE SEALS CANNOT BE RELIED ON NOT TO LEAK. ANY SUCH LEAKS INTO THE COLD BOX REDUCE THE EFFECTIVENESS OF THE INSULATION, THEREBY REDUCING THE EFFICIENCY OF THE REFRIGERATOR. WELDEDJOINTS MAKE REPLACEMENT OF COMPONENTS DIFFICULT AND HAVE ...

The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

UP TO 35,000 WORKERS OF THE U.S. CHEMICAL INDUSTRY AND MORE THAN 270,000 WORKERS IN THE PETROLEUM AND COAL-RELATED INDUSTRIES MAY BE EXPOSED DAILY TO CARCINOGENIC AND MUTANOGENIC COMPOUNDS FROM THE AROMATIC AMINE GROUP. COAL GAS, INC. DEVELOPED A VERY SIMPLE HIGH-TECHNOLOGY APPROACH TO MONITORING THE EXPOSURE OF PERSONNEL TO TRACE LEVELS OF POLLUTANTS AND IS PROPOSING TO CONDUCT R & D WHICH WILL E ...

75225S The elevated level of vibrations complicates the achievement of sub-nanometer stability for the final focusing lenses in supercolliders. This project will develop a radiation-hardened seismic (vibration) sensor, with sub-nanometer precision and fully immune to strong magnetic fields, for monitoring the stability of the final focusing lenses. In Phase I, two electrochemical prototype sens ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...