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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human Services
  2. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  3. Short-Range Ultra-Low-Cost Anti-Submarine Sensors

    SBC: BROWN COMPUTER CO.            Topic: SB031023

    Insuring the safety and control of littoral waters is problematic because of the difficulties of surveillance. The preferred methods of surveillance in the ocean are acoustic. In littoral waters, acoustic methods fail because noise from the surf and reflections from the shallow bottom convolute acoustic signatures beyond our capacity to discern them. Water absorbs light, reducing the effectiven ...

    SBIR Phase II 2005 Department of DefenseDefense Advanced Research Projects Agency
  4. THERMOSYPHON TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human Services
  5. REGENERATIVE TURBINE TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human Services
  6. ENHANCING PEPTIDE DELIVERY TO THE BRAIN

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is the leading cause of death and disability in the US with an incidence rate of 1.5 million at cost of $56.3 billion annually. There is no treatment for TBI, and the lack of therapeutic intervention for a public health issue of this magnitude constitutes a healthcare crisis. We have developed COG133, a peptide that is neuroprotecti ...

    SBIR Phase II 2005 Department of Health and Human Services
  7. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human Services
  8. Nanostructured active layers for deep-green light emitting diodes (LED)

    SBC: Dot Metrics Technologies, Inc.            Topic: SB032029

    In phase I, Dot Metrics Technologies demonstrated the feasibility of a new method of introducing deep-green luminescent nanostructure into semiconductor materials for light-emitting device applications. The materials were used to fabricate and characterize preliminary optoelectronic device test structures. In phase II, Dot Metrics Technologies proposes to leverage these new materials and methods i ...

    SBIR Phase II 2005 Department of DefenseDefense Advanced Research Projects Agency
  9. ELCA ASSAY OF CLINICALLY IMPORTANT CLOTTING FACTORS

    SBC: Elcatech, Inc.            Topic: N/A

    A NEW TECHNIQUE HAS BEEN DEVELOPED TO ASSAY CLOTTING FACTORS: SOLID-PHASE FIBRINOGEN AND LABELLED FIBRINOGEN TOGETHER ARE USED AS A SUBSTRATE TO DETECT THROMBIN GENERA- TED FROM THE CLOTTING CASCADE. WHEN THROMBIN CLEAVES BOTH FORMS OF FIBRINOGEN TO FIBRIN, THE LABELLED FIBRIN IN SOLU- TION ASSOCIATES WITH THE SOLID PHASE. THIS TECHNIQUE, WHICHHAS BEEN NAMED "ENZYME-LINKED COAGULATION ASSAY" OR EL ...

    SBIR Phase II 1987 Department of Health and Human Services
  10. Replication of the Human Secretory Pathway in Yeast

    SBC: Glycofi, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): With its ability to secrete high levels of recombinant proteins, the yeast Pichia pastoris is extensively used for protein manufacturing. However, as actual yields vary widely for individual proteins, GlycoFi is focusing on the improvement of protein yields in P. pastoris as part of the company's long term mission to develop yeast-based protein production tech ...

    SBIR Phase II 2005 Department of Health and Human Services
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