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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Monitoring Food and Water for Pathogens

    SBC: BIOSCALE, INC.            Topic: CBD03201

    Having achieved or exceeded all goals and objectives of the Phase I research program, BioScale has thus demonstrated feasibility of a multiplexed, immuno-electromechanical pathogen detection method. In Phase II, BioScale proposes to advance this research by assembling a complete assay system that integrates discrete, commercial off the shelf (COTS) sample preparation subcomponents with the propri ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  3. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. Model-Based Design of Test Systems for Chemical Protective Clothing

    SBC: CREARE LLC            Topic: CBD02202

    The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  5. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. In Vivo Molecular Imaging of Cancer in Small Animals

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Murine models of cancer now have an essential role in formulating modern concepts of carcinogenesis and metastasis, and provide us with a realistic means of developing and evaluating new diagnostic and therapeutic techniques. Moreover, transgenic and knock-out techniques for manipulating the genome allow us to tailor animal models that accurately recapitulate ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. High Resolution Small Animal SPECT

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I: SPECT is non-invasive imaging technique which provides an image of the three dimensional distribution of radionuclide in any slice through an organ under study. These images allow investigation of metabolism in the region being studied and are a useful tool for diagnosing symptoms of diseases such as cancer and myocardial ischemia. SPECT is also showin ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. High Sensitivity X-ray Detector for PET/CT

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Dramatic advances in imaging technology, especially for small-animal imaging, have been an important driving force in establishing the field of molecular and genomic imaging. One of these new technologies, microPET, has demonstrated a tremendous potential in the study of small animal models, allowing the measurement of biological parameters and permitting i ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. A Fast, High Luminosity Scintillator for PET

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a nuclear imaging modality that makes use of a range of positron-emitting tracers to provide images that reflect different parameters relevant to tumor biology. Tumor cells generally differ from normal cells in many respects, including rates of glucose utilization, proliferation and protein synthesis. PET tracers such as ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Development of an anti-malaria toxin vaccine candidate

    SBC: ANCORA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Malarial disease represents one of the most pressing medical healthcare issues facing the world today. While limited drug treatment options exist, a vaccine solution is widely considered as one of the most effective therapeutic weapons to combat malaria. Despite years of research, though, malarial vaccine initiatives have yet to produce a viable candidate. One ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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