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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. In Vivo Molecular Imaging of Cancer in Small Animals

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Murine models of cancer now have an essential role in formulating modern concepts of carcinogenesis and metastasis, and provide us with a realistic means of developing and evaluating new diagnostic and therapeutic techniques. Moreover, transgenic and knock-out techniques for manipulating the genome allow us to tailor animal models that accurately recapitulate ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. High Resolution Small Animal SPECT

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I: SPECT is non-invasive imaging technique which provides an image of the three dimensional distribution of radionuclide in any slice through an organ under study. These images allow investigation of metabolism in the region being studied and are a useful tool for diagnosing symptoms of diseases such as cancer and myocardial ischemia. SPECT is also showin ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. High Sensitivity X-ray Detector for PET/CT

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Dramatic advances in imaging technology, especially for small-animal imaging, have been an important driving force in establishing the field of molecular and genomic imaging. One of these new technologies, microPET, has demonstrated a tremendous potential in the study of small animal models, allowing the measurement of biological parameters and permitting i ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. A Fast, High Luminosity Scintillator for PET

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a nuclear imaging modality that makes use of a range of positron-emitting tracers to provide images that reflect different parameters relevant to tumor biology. Tumor cells generally differ from normal cells in many respects, including rates of glucose utilization, proliferation and protein synthesis. PET tracers such as ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of an anti-malaria toxin vaccine candidate

    SBC: ANCORA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Malarial disease represents one of the most pressing medical healthcare issues facing the world today. While limited drug treatment options exist, a vaccine solution is widely considered as one of the most effective therapeutic weapons to combat malaria. Despite years of research, though, malarial vaccine initiatives have yet to produce a viable candidate. One ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Kilo-base Range Isothermal DNA Amplification

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to amplify and subsequent detection a target sequence with a limited length may satisfy the need for diagnosing some of the diseases. Nevertheless, much biomedical research, such as cloning genes and analysis of genetics variation, often demands selective amplification of large DNA fragments in the kilo basepairs range. Currently Polymerase Chain R ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Monitoring Food and Water for Pathogens

    SBC: BIOSCALE, INC.            Topic: CBD03201

    Having achieved or exceeded all goals and objectives of the Phase I research program, BioScale has thus demonstrated feasibility of a multiplexed, immuno-electromechanical pathogen detection method. In Phase II, BioScale proposes to advance this research by assembling a complete assay system that integrates discrete, commercial off the shelf (COTS) sample preparation subcomponents with the propri ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. A Nanofibrous Biocomposite Small-Diameter Graft

    SBC: BIOSURFACES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is no small-diameter (< 5mm internal diameter) vascular prosthesis approved for clinical use in small vessel reconstruction. Current prostheses are not capable of emulating the biological and physical properties of the normal arterial wall, resulting in high failure rates. In phase I, a nanofibrous biocomposite small-diameter vascular graft comprised o ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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