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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Synthesis and Evaluation of a Novel Anti-HIV Agent

    SBC: Kucera Pharmaceutical Company            Topic: N/A

    The long-term goal of this research is to develop a drug that is safe and effective against drug-resistant human immunodeficiency virus (HIV) infection. Several challenges confront current anti-HIV chemotherapy. The frequency of drug-resistant and multidrug-resistant HIV-1 is increasing. Toxicities associated with current HIV medications often result in the discontinuation of these therapies. Phys ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. A Wide Band Reflectance- DPOAE (WR-DP) Screener

    SBC: Mimosa Acoustics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of newborn hearing screening is to identity infants with inner ear pathology (IEP), but most neonates who fail screening have conductive disorders (CD) rather than IEP, resulting in high false positive rates and costly follow-up diagnostic evaluation. The Rhode Island study (1993) has shown that the prevalence of conductive disorders (CD) over inner ea ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Assay for Measurement of PCB Aroclors

    SBC: SYNTHERICA CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Polychlorinated biphenyls (PCBs) are a major public health hazard. We intend to develop the novel Synthetide(tm)-based test array described in Phase I for the measurement of polychlorinated biphenyls (PCBs) in the

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Pretest Probability Assessment for Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Pretest probability assessment (PTP) plays a pivotal role in the evaluation of pulmonary embolism (PE) in the emergency department (ED) and accurate PTP assessment can modify defensive test-ordering behavior by physicians. However, current methods of PTP assessment produce broad categories of risk that tend to over fit individual patients and seldom obviate tes ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Pretest Probability Assessment for Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Pretest probability assessment (PTP) plays a pivotal role in the evaluation of pulmonary embolism (PE) in the emergency department (ED) and accurate PTP assessment can modify defensive test-ordering behavior by physici

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  7. ENHANCING PEPTIDE DELIVERY TO THE BRAIN

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is the leading cause of death and disability in the US with an incidence rate of 1.5 million at cost of $56.3 billion annually. There is no treatment for TBI, and the lack of therapeutic intervention for a public health issue of this magnitude constitutes a healthcare crisis. We have developed COG133, a peptide that is neuroprotecti ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Crossroads: Cooperative High School Drug Prevention

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Adolescent drug use continues to be a major public health problem. The need for late onset drug prevention and early cessation in high schools is great, yet few universal programs exist that target alcohol, tobacco, and other drug use among high school students. Crossroads is a universal drug prevention program based on a cooperative relationship between high s ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Crossroads: Cooperative High School Drug Prevention

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Adolescent drug use continues to be a major public health problem. The need for late onset drug prevention and early cessation in high schools is great, yet few universal programs exist that target alcohol, tobacco, and other drug use among high school students. Crossroads is a universal drug prevention program based on a cooperative relationship between high s ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Educational Opportunities for Youth in Foster Care

    SBC: INDEPENDENT LIVING RESOURCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this project is to produce, test, and evaluate the use of a multimedia program for foster youths and adults who care for them. The program will connect foster and group home residents (youths), foster and group home parents, other caregivers, and youth serving professionals with information and resources to make post secondary educational opportu ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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