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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Knowledge Management System for Multilingual Health Content

    SBC: Transcendent International, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed project is to develop an advanced, web-based knowledge management system for the creation and distribution of multilingual, patient-oriented documents. The system provides a vast library of pre-translated documents and document templates for medical, educational, and administrative materials used in patient-care. System users will be abl ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Hepatitis C Virus Inhibitors

    SBC: PROGENICS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development of new therapeutic agents for Hepatitis C virus (HCV) infection is a major public health priority. It is estimated that 170 million people worldwide, including approximately 4 million individuals in the United States, are infected with HCV. Available therapies are non-specific antiviral agents with modest efficacies and significant toxicities. W ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Broad Detection System for Tick-Borne Pathogens

    SBC: Bioscience Development Inc            Topic: N/A

    DESCRIPTION (provided by applicant): There is an increasing number of cases and spread of Lyme and other tick-borne diseases in the United States. The same tick that can transmit the agent of Lyme disease, Borrelia burgdorferi, can simultaneously transmit other pathogens such as Babesia, Anaplasma, and Rickettsia. This is of great concern to the public and their physicians. This concern is reflect ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Photoacoustic CT for Preclinical Molecular Imaging

    SBC: OPTOSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this collaborative research project is to commercialize a prototype photoacoustic computed-tomography (PCT) scanner for conducting preclinical molecular imaging. This scanner has been developed by OptoSonics with funding from a Fast Track SBIR grant from the National Cancer Institute (R44-CA-102891) and additional private funding fro ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Koning Cone Beam Breast CT

    SBC: KONING CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to continuously develop a novel cone beam breast computed tomography system (Koning CBCT 1000) into a clinically useful diagnostic breast-imaging tool and accelerate the FDA market clearance process to commercialize this cutting edge technology for diagnostic breast imaging. A commercial grade clinical scanner has been designed and c ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Safety and PK Study in Hepatic Impairment Patients

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Liver fibrosis, a disease affecting tens of millions of patients worldwide, is the liver scarring response to chronic injury from viral hepatitis B or C, excessive alcohol use, iron overload or extrahepatic obstructions and can progress to liver cirrhosis, liver failure and death. In fact, deaths from complications of liver fibrosis/cirrhosis are expected to tr ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Influenza Virus-Like Particle (VLP) Vaccines

    SBC: TECHNOVAX INC            Topic: N/A

    DESCRIPTION (provided by applicant): Influenza virus-like particles (VLPs) have demonstrated in preclinical studies that they are highly immunogenic and efficacious in protecting against influenza infections. This emerging vaccine technology not only creates new vaccine candidates with alternative routes of administration (intranasal or intramuscular) but also implements a fast, flexible, and depe ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Performance Evaluation of MiTiHeart LVAD

    SBC: MOHAWK INNOVATIVE TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed Competing Continuation is to develop and incorporate into the MiTiHeart LVAD those elements necessary to meet the requirements for FDA IDE application. In support of this goal and based on initial FDA communications, it has been determined that the addition of a validated electronic controller and power supply system to ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Rapid test for leptospirosis

    SBC: CHEMBIO DIAGNOSTIC SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Leptospirosis is a life-threatening zoonotic infection that causes acute renal failure and pulmonary hemorrhage. In the US, human leptospirosis is an emerging disease due to outbreaks that have occurred during disasters and sporting events and the increase in travel and recreation-related exposures. Furthermore, leptospirosis is a neglected disease which impa ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  10. TRANSGENIC PRODUCTION OF CD4-IGG2 FOR HIV THERAPY

    SBC: PROGENICS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A major goal of HIV-1 research is the development of nontoxic agents that target novel stages of the viral replicative cycle, such as viral entry. New agents are needed both to combat the growing incidence of HIV-1 strains that are broadly resistant to existing antiretroviral medications and to lessen the considerable toxicities associated with current therapi ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
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