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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Paperless Quality Donor System with Decision Making

    SBC: Talisman, Ltd            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objectives of this project are to improve the safety and availability of the US blood supply. The principal aim of this SBIR Competing Continuation Phase II Proposal for a Paperless Quality Donor System with Decision Making is to complete the development of its Quality Donor System(tm) (QDS) and to secure ongoing 510(k) clearances for it from t ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Gene Based Therapy for Congestive Heart Failure P2 SBIR

    SBC: Nanocor Therapeutics, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Congestive heart failure is a major cause of morbidity and mortality in the United States. While progress in conventional treatments is making steady and incremental gains to reduce heart failure mortality, there is a critical need to explore new therapeutic approaches. It is now apparent that gene therapy has broader potential in diseases such as congestive he ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. CG-GRID: Computational Genetics Grid Resource for Interaction Discovery

    SBC: PARABON COMPUTATION, INC.            Topic: 400

    DESCRIPTION provided by applicant Advances in DNA sequencing technology have now made it practical and affordable to generate datasets containing millions of genetic attributes that can be tested for association with disease susceptibility The computational complexity of searching for genetic interactions over such high dimensional datasets imposes great challenges for genome wide associatio ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Peptide-coated skin substitutes for the treatment of burn injuries and wounds

    SBC: AFFINERGY, LLC            Topic: 300

    DESCRIPTION provided by applicant Burn injuries and chronic wounds present a significant burden to patients and the US healthcare system Each year in the US there are burns that require medical treatment and burn patients that require hospitalization The mortality rate associated with severe burns can be as high as with of patient deaths arising from infection In add ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease

    SBC: Immunext, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Systemic lupus erythematosus SLE is a devastating autoimmune disease that most commonly affects women in their child bearing years SLE attacks multiple organ systems but renal and neurologic involvement are the usual harbingers of poor outcome Despite effective albeit toxic immunosuppressive therapy only of patients with these serious manifestations ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Novel therapeutics for fatty liver disease and type-II diabetes

    SBC: SOUTHEAST TECHINVENTURES INC            Topic: 200

    DESCRIPTION provided by applicant Western lifestyle and diet have spurred the growth of numerous obesity related disorders in the US including metabolic syndrome and type diabetes to epidemic proportions However less well known is the rising epidemic of non alcoholic fatty liver disease NAFLD NAFLD ranges from mild hepatosteatosis to severe fibrosis or cirrhosis and is initially charac ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a drug discovery platform for human islets

    SBC: Zen-Bio, Inc.            Topic: 200

    DESCRIPTION provided by applicant Diabetes and diabetes related co morbidities are at epidemic proportions and an enormous burden to our healthcare system Although there has been significant progress in defining the causative factors and molecular mechanisms involved in both type and type diabetes it remains an overwhelming challenge to identify efficacious therapeutic modalities Novel a ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Digital Video Monitor and Analysis of Seizures with EEG

    SBC: Clever Systems, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): we propose to develop a completely functioning prototype system for automated and high-throughput seizure detection and classification in animals, mainly in mice or rats or guinea pigs, based on semiology (video record). The purposes of the project are to first develop technologies and tools that can automatically detect seizures through visual observation; th ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Virtual Occupational Therapy Assistant (VOTA)

    SBC: BARRON ASSOCIATES, INC.            Topic: NICHD

    DESCRIPTION provided by applicant The Virtual Occupational Therapy Assistant VOTA will enable stroke patients to practice activities of daily living ADLs as part of an in patient skilled nursing outpatient home health and or teletherapy rehabilitation program The system leverages low cost human motion tracking advanced kinematic pose estimation algorithms and state of the art game e ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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