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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel technologies to remove obscuring blood from fine needle aspiration biopsies

    SBC: AFFINERGY, LLC            Topic: NIGMS

    SUMMARY ABSTRACT Fine needle aspirationFNAcytology is the standard technique for evaluating thyroid nodulesHemorrhaging is common during the procedurehoweverleading to an aspirate that is significantly diluted by bloodSubsequent slide preparations are often suboptimalresulting in nondiagnostic outcomes that necessitate additional testing or diagnostic surgeryIn factquality is so unpredictable that ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Medical Images HTML and Clinical Trial Remote Collaboration

    SBC: HEART IMAGING TECHNOLOGIES, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Medical drugs and devices are regulated by the U S Food and Drug Administration FDA based on data from multicenter clinical trials In U S spending on clinical trials was approximately $ billion Over the past decade the efficiency of clinical trials has been improved by electronic data capture EDC systems whose use has increased from to ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Therapeutic Vaccine Targeting CMV Antigens in Glioblastoma

    SBC: Annias Immunotherapeutics, Inc.            Topic: NCI

    DESCRIPTION provided by applicant Malignant primary brain tumors represent the most frequent cause of cancer death in children and young adults and account for more deaths than cancer of the kidney or melanoma Glioblastoma GBM is uniformly lethal and current therapy is non specific and produces a median overall survival of andlt months In contrast immunotherapeutic approaches are exq ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Clinical Evaluation of T3D-959 as a Potential Disease Remedial Therapeutic for the Treatment of Alzheimer's Disease

    SBC: T3D Therapeutics, Inc.            Topic: NIA

    DESCRIPTION provided by applicant The purpose of the proposed project is to conduct a Phase a mechanistic clinical proof of concept study of an investigational drug T D which is being developed for the treatment of cognitive and functional decline in Alzheimerandapos s disease patients T D has successfully completed Phase I studies and with data demonstrating robust entry into the b ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Digital Star HIV Prevention for Youth in Mental Health Treatment

    SBC: VIRTUALLY BETTER INC            Topic: 105

    DESCRIPTION provided by applicant Adolescents in mental health treatment are at greater risk for HIV and other STIs than their peers due to an earlier age of onset of sex less protected sex more sexual partners and more frequent substance use This greater risk is due to multiple factors including cognitive misperceptions affect dysregulation and less self efficacy The numerous adolescent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. External, High-Intensity Proton Injector with Ultra-Precise Control for Fast Spot Beam Scanning PBRT

    SBC: T Antaya, LLC            Topic: 102

    DESCRIPTION provided by applicant Proton therapy particle accelerators usually cyclotrons are large and expensive devices and only about of proton therapy treatment candidates have access to proton therapy The research at Antaya Science and Technology aims to reduce the overall cost simplify the operation and increase the availability of proton therapy to all candidate patients The p ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Biguanides to Treat Type 2 Diabetes

    SBC: NOVATARG, INC.            Topic: 200

    DESCRIPTION provided by applicant The present Phase SBIR application builds on the previous Phase SBIR award to identify a markedly improved biguanide to replace metformin in the treatment of T D Over new biguanides were synthesized in the Phase work and analyzed for their ability to produce metformin like activity in cells and animal models but at a much lower effective concentratio ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Novel and Kidney Selective AMPK Activators to Treat Polycystic Kidney Disease

    SBC: NOVATARG, INC.            Topic: 400

    DESCRIPTION provided by applicant Autosomal dominant polycystic kidney disease ADPKD is characterized by the presence of innumerous fluid filled cysts that progressively enlarge leading nephron loss and the progressive decline in renal function Aberrant proliferation of the cyst lining epithelial cells and the accumulation of fluid within the cysts du to Cl dependent fluid secretion are res ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. IGF OT IGF Fluorescent Nanodiamonds for In Vitro and In Vivo Biological Imaging SBIR Topic Phase II

    SBC: ADAMAS NANOTECHNOLOGIES INC            Topic: NHLBI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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