Award Data

Chemical, biological, or toxin attacks in military and civilian settings are a serious and growing concern. Standard first aid for exposure to some chemical warfare agents and toxins includes the immediate administration of relevant antidotes using an autoinjector. When an attack occurs, pre-filled autoinjectors must be immediately available and thus highly portable, and they must be suitable fo ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. Existing protein purification methods primarily rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermeasures to chemical and biological threats. To overcome these limitations, the overall goal of th ...

Safe and efficient ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these limitations, we propose to develop and demonstrate a novel bioaerosol ionization and collectio ...

Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare proposes to develop a hermetic garment closure system that seals macroscopic and microscopic gaps at interfaces and closures and pro ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

This Phase II SBIR proposal is for the development of a miniaturized real-time visible/UV spectrometer prototype based on micro-opto-electro-mechanical systems (MOEMS) technology. Use of MOEMS technology enables orders of magnitude reductions in size, we

In the wake of the September 11th attacks and subsequent Anthrax scares, researchers worldwide are working to expand our ability to rapidly assess what poses a terrorism threat to the public. The rapid detection of specific pathogens is required for biod