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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Ab-Initio Geometry Optimization of Large Molecules

    SBC: Q-CHEM, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Density-Functional Theory (DFT) is highly desirable for modeling biomolecules due to its accuracy. While DFT calculations of the energy are now common for large molecules, the use of DFT geometry optimizers is still confined to relatively small molecules containing no more than thirty atoms. The key limitation is that the number of steps required to reach the o ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. A cell-free system for assaying ion channel function

    SBC: INTEGRAL MOLECULAR, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Ion channels function as cell-signaling effectors for a diverse range of physiological activities, including nerve signal propagation, muscle contraction, cardiopulmonary regulation, and cell metabolism. Their impact on human health is underscored by the existence of forty compounds, including about 15% of the top 100 best-selling drugs, that target ion channe ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA

    SBC: THREE C INSTITUTE FOR SOCIAL DEVELOPMT            Topic: N/A

    Location 1903 N HARRISON AVE, STE 101 CARY, NC 27513 United States N44MH0664102C $365 147.00 2 005 ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA Department of Health and Human Services National Institutes of Health SBIR PHS2006-1 THREE C INSTIT ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Technology for Administration of the Teen-ASI

    SBC: Health Outcomes Inc            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to conduct a clinical trial using a suite of web-based software products as well as a web portal that will help with standardized assessment, treatment planning, referral, and outcomes tracking for adolescent substance abuse treatment. Products will include the automated Internet version of the Self- Report Teen-Addiction Severity Index (SR-T-ASI Net ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. All Stars Technology: Web-Based Program Enhancements

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The success of research-based prevention programs depends on the degree to which they are implemented with fidelity. This Phase II project will enhance All Stars, a drug abuse prevention program, by integrating web-based and multimedia technologies. Enhancements will improve program fidelity by making the program easier to deliver. They will improve effectivene ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. An Aerosol Device for Measles Vaccination (B)

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Antisense Treatment for Thalassemia. Preclinical study.

    SBC: ERCOLE BIOTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Antisense Treatment for Thalassemia. Preclinical study.

    SBC: ERCOLE BIOTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Branched Outcomes Instrument for Mental Health Service

    SBC: Health Outcomes Inc            Topic: N/A

    DESCRIPTION (provided by applicant): In its Roadmap Initiatives, NIH has highlighted the need for improvement in dynamic assessments in health care and for the use of new technology in the collection of patient-reported outcomes (PRO). The goal of this project is to further validate a new mental health outcomes-tracking instrument for depression, anxiety, social functioning, and occupational funct ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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