Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

In Phase I, Nomadics demonstrated that a novel chemical weapon indicating chromophore (CWIC) developed by Professor Tim Swager at MIT will allow equipment to be quickly and easily examined to show any areas of contamination, making targeted decontamination manageable. When exposed to CW agent simulants, CWICs react to become fluorescent under UV stimulation. In the first phase, we implemented a s ...

The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

By continuing teaming up with one of the most reputable university teams in THz science and technology, ArkLight proposes to carry out the tasks set for a Phase-II program following our success in Phase I. We are aimed at the further development of novel spectrometers to analyze chemicals in the vapor phase based on accurate measurements of the emission and absorption spectra due to the molecular ...

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CURRENT MORPHOMETRY AND IMAGE ANALYSIS SYSTEMS CAN BE BROADLY DIVIDED INTO THOSE WHICH DISPLAY AN IMAGE AND REQUIRE THE USER TO TRACE THE POINTS OR LINES CONSIDERED SIGNIFICANT, AND THOSE WHICH APPLY COMPLEX ALGORITHMS TO LOCATE SIGNIFICANT OBJECTS AUTONOMOUSLY. WE SEE A NEED FOR AN INTERMEDIATE TYPE OF SYSTEM IN WHICH THE USER COULD RAPIDLY INDICATE THE APPROXIMATE LOCATION OF SIGNIFICANT OBJECTS ...

CONSIDERABLE EVIDENCE EXISTS THAT ANALYSIS OF THE ELECTRO- CARDIOGRAM OVER EXTENDED PERIODS OF TIME PROVIDES CLINICALLYSIGNIFICANT INFORMATION IMPORTANT IN THE DIAGNOSIS AND TREATMENT OF CARDIAN DISEASE. AVAILABLE AMBULATORY MONITOR-ING DEVICES ARE ADEQUATE FOR 24-HOUR PERIODS; LIMITATIONS ARE EVIDENT WHEN LONGER PERIODS ARE REQUIRED. THE PROJECT WILL ESTABLISH THE FEASIBILITY OF BIOLOGICAL DATA A ...

DESCRIPTION (provided by applicant): There is growing recognition that surgical repair of the heart is most likely to be successful in infancy (when there is dramatic capacity for growth and remodeling). For a subset of patients, the optimal time for intervention is prior to birth. Current prenatal cardiac intervention (PCI) procedures clearly have technical limitations in both fetal visualizat ...

DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...