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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The great need for more efficient and effective oncologic drug development has driven the discovery and integration of biomarkers into all phases of clinical research. Further still, biomarkers are entering the clinical arena as early means of determining which patients are likely benefiting from a particular drug. One field of targeted therapy that has relied ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years of age have at least moderate periodontitis with over a quarter having lost their teeth, resulting in serious health a nd quality of life repercussions. Bone grafting is routinely necessary prior to the placement of Dental implants due to bone loss caused by per ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Point of Care Attachment of Antibiotics onto Metal Implants

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio ns, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significa ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Click Chemistry for Immobilized Bone Morphogenetic Protein

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Growth factors are potent signaling molecules, initiating essential cellular programs for differentiation, proliferation and survival. Only recently have large molecules like growth factors, been employed to enhance the efficacy and specificity of medical implant therapies. In particular, procedures that require native tissues to interact with an implanted mat ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Innovative Tools for the Molecular Diagnosis of Cancer

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Cancer Institute has called for new tools for cancer research and diagnosis that are accurate, practical and affordable. Alderon Biosciences, Inc. proposes to fill this need by developing an open biosensor platform technology for quantitative studies of cancer gene expression, with the goal of replacing slower and more costly methods. The working ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. THERMOSYPHON TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. REGENERATIVE TURBINE TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Medical Student Education on Alcohol Abuse and Dependence

    SBC: Clinical Tools, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): This is a competitive revision application in response to NOT-OD-09-058 NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications . Medical schools provide little background and training to prepare future physicians to deal with alcohol misuse, abuse and dependence seen in the population. To address this need we are current com ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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