Award Data

Sequencing the human genome has uncovered numerous putative novel targets for which 3D structures are not available and which have no known inhibitors. We proposed a system to use computational methodologies to generate 3D molecular models of target proteins, and to use these models to design novel chemical inhibitors. Currently, the system is capable of accurately folding a target's amino acid se ...

The goal of this project is to design, build, and test an active electromagnetic induction (EMI) sensor array for detecting and characterizing IEDs. At low frequencies (below a few kHz), an EMI sensor is a magnetometer that primarily responds to susceptibility targets (i.e., ferrous objects). The main difference is that, while a magnetometer uses the earth's field as the illuminating source, an EM ...

The goal of this project is to design, build, and test an active electromagnetic induction (EMI) sensor array for detecting and characterizing IEDs. At low frequencies (below a few kHz), an EMI sensor is a magnetometer that primarily responds to susceptibility targets (i.e., ferrous objects). The main difference is that, while a magnetometer uses the earth’s field as the illuminating source, an ...

The Army seeks to standardize all equipment on its battlefield logistics fuel, JP-8. JP-8 is difficult to use for small-scale, low-power applications, however, since its low vapor pressure and complex composition inhibit complete vaporization. Existing methods for vaporizing logistics fuels are not sufficiently controllable to support highly efficient catalytic combustion processes, or impose un ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

Thermal batteries are the power source of choice for many weapon systems. While thermal batteries offer designers several key advantages, the design and integration of this technology into new applications suffers from two significant impediments. The first is the lack of suitable design tools, and the second is the time-consuming and expensive effort necessary to qualify a new battery design thro ...

Accurate estimations of the height and velocity of precision airdrop systems are required to control final deceleration maneuvers. Airdrop systems have a limited deceleration window, so robust and reliable estimations are required. Radar, sodar, and lidar sensors have been evaluated for this role with varying degrees of success. Foliage and vegetation prove troubling for many of the sensors. H ...

A recent increase in the occurrence of pilot parachute deployment hesitation events during training has focused attention on the flow field about parachutists in freefall. An improved understanding of this flow will contribute to better equipment and improved safety. Computational Fluid Dynamics (CFD) analysis is a powerful technique for exploring such flows. Once validated against experimental d ...

Provision of clean drinking water poses a significant challenge to Army units in the field. Due to the quantity of water required and its substantial weight, soldiers can only carry a limited supply, and sustainment of soldiers through centralized resupply poses major logistical hurdles in many situations. Existing portable water filters to not meet the need to treat locally available water supp ...

Creare proposes to complete the development of a system that will simultaneously enable two-way voice communication while monitoring sound exposure to the ear for soldiers working in high noise environments. Current Army artillery crews are forced to work in close proximity to cannons that produce in excess of 180 dB of impulsive noise, which can result in noise-induced hearing loss after brief e ...