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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Gene Expression Signatures to Predict Treatment Response in Systemic Sclerosis

    SBC: CELDARA MEDICAL, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant Today systemic sclerosis SSc clinical trials generally include all subsets some may benefit others do not confounding measures of efficacy Because each expression subset has a different underlying deregulated molecular pathway no single drug is expected to benefit all patients i e rational patient selection is required to facilitate drug development F ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. See It Be It: Interactive Technology to Increase School Engagement and Prevent Dropout

    SBC: 3-C Institute for Social Development, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant Dropping out of school costs the nation up to $ billion annually in lost wages unemployment incarceration costs welfare dependence and health care costs Moreover poorer individual health and well being result from dropping out Despite recent reductions in the total number of dropouts minority students remain twice as likely to drop out as White stud ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease

    SBC: Immunext, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Systemic lupus erythematosus SLE is a devastating autoimmune disease that most commonly affects women in their child bearing years SLE attacks multiple organ systems but renal and neurologic involvement are the usual harbingers of poor outcome Despite effective albeit toxic immunosuppressive therapy only of patients with these serious manifestations ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Novel therapeutics for fatty liver disease and type-II diabetes

    SBC: SOUTHEAST TECH INVENTURES            Topic: 200

    DESCRIPTION provided by applicant Western lifestyle and diet have spurred the growth of numerous obesity related disorders in the US including metabolic syndrome and type diabetes to epidemic proportions However less well known is the rising epidemic of non alcoholic fatty liver disease NAFLD NAFLD ranges from mild hepatosteatosis to severe fibrosis or cirrhosis and is initially charac ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Wireless and Noise Attenuating Headset for Automated Hearing Screening

    SBC: CREARE LLC            Topic: NIDCD

    DESCRIPTION provided by applicant Hearing loss is a leading public health concern with about of American adults reporting some degree of impairment Of those fewer than seek help for their condition for a variety of reasons To address this issue the National Institue of Deafness and Other Communication Disorders NIDCD is seeking solutions to improve hearing healthcare access and l ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. TheraSense Dynamic Support Surface for Pressure Ulcers

    SBC: Simbex LLC            Topic: 600

    DESCRIPTION provided by applicant The Principal Objective of this Fast Track SBIR project is to develop and validate a cost effective commercial product TheraSenseandquot a highly innovative active support surface bed system for the treatment and prevention of serious decubitus ulcers commonly known as bed sores or pressure ulcers Current advanced bed systems for both institutional and ho ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. A Quantitative Optical Sensor to Monitor Tumor Vascular Physiology

    SBC: Zenalux Biomedical, Inc.            Topic: 102

    DESCRIPTION provided by applicant In there were new cases of head and neck cancers HNC in the United States Early detection of new and locally recurrent cancers is clinically important to reduce not only cancer related mortality but also treatment associated morbidity as it impacts multiple organ functions including respiration olfaction hearing eating swallowing and speak ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Elementary School Mindfulness-Based Substance Use Prevention Program

    SBC: Innovation Research And Training, Inc.            Topic: 400

    DESCRIPTION provided by applicant The proposed project will complete the development of and evaluate the efficacy of Master Mind a mindfulness education substance abuse prevention for late elementary school aged children Past research has found that mindfulness has many benefits for youth such as increases in attention social competence and emotion regulation as well as decreases in stres ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Game-based Skills Development in Alcohol Assessment and Intervention

    SBC: Clinical Tools, Inc            Topic: 400

    DESCRIPTION provided by applicant The Clinical Challenge Alcohol project seeks to improve outcomes of patients with at risk alcohol use or an alcohol use disorder by improving the alcohol assessment and intervention skills of medical students To accomplish this goal we will build upon our platform independent Clinical Encounters D Patient Training Environment This project expands the Clinic ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Integration of Genomic Biomarkers with the devTOX Human Embryonic Stem Cells Scre

    SBC: Integrated Laboratory Systems, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant In utero exposure to environmental chemicals or drugs accounts for approximately of all birth defects and can have an impact in adult life by disrupting the epigenetic developmental programs that are activated later in life e g puberty aging The currently accepted regulatory test for identifying potential teratogens involves the use of thousands of ani ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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