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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A crosslinked cartilage-derived matrix for cartilage tissue engineering

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    Abstract OsteoarthritisOAremains a significant source of significant pain and disabilityaffecting overmillion adults with an economic burden of over $billion per year to the USJoint replacement is a well established procedurebut its finite life span makes this treatment unacceptable for younger or more active individualswho often require additional revision surgeries as they ageBoth complicated re ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. An Aerosol Device for Measles Vaccination (B)

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. A Phase III Trial to Validate HP 129Xe MRI as a Functional Pulmonary Biomarker in Pediatric Lung Disease

    SBC: POLAREAN, INC.            Topic: NHLBI

    PROJECT SUMMARYABSTRACT Chronic respiratory diseasessuch as COPDasthmaand cystic fibrosisCFare therd leading cause of death in the USwith costs exceeding $B yearA major obstacle to evaluate therapies for these diseases is that currently available tools to assess lung function are either insensitive to early disease or unsuitable for longitudinal useThough ubiquitouspulmonary function testing via s ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a mobile and automated platform for multiplexed multi-modality imaging

    SBC: Sonovol, Inc.            Topic: 102

    Abstract Bioluminescence imagingBLIsystems are installed in thousands of facilities and labsand with their straightforward and low cost workflow for longitudinal studiesare the most commonly used preclinical modality for assessing tumor models in rodentsThere currently is no high throughput and low cost system enabling BLI images to be combined with anatomical images of soft tissue to confirm tumo ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Functional Tissue Engineering for Cartilage Repair

    SBC: Cytex Therapeutics, Inc.            Topic: NIA

    Abstract It is estimated that only aboutof young patients suffering from!activity limiting hip osteoarthritisOAchoose to undergo traditional hip replacement surgeryThis low percentage is attributed to the shortened projected lifetime of hip implants for active patients and the subsequent need for revision surgeries that are plagued with higher complication rates and overall decreased effectiveness ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Model-Based Design of Test Systems for Chemical Protective Clothing

    SBC: CREARE LLC            Topic: CBD02202

    The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Novel technologies for detection of podocytes from preeclamptic patients

    SBC: AFFINERGY, LLC            Topic: NICHD

    Preeclampsia is a complication of pregnancy characterized by elevated blood pressureproteinuriaand endothelial dysfunction involving multiple organ systemsWorldwidepreeclampsia is the largest cause of fetal and maternal morbidity and mortalityand accounts for nearlyof maternal deaths in the United States alone each yearCurrentlythere is no approved diagnostic test to predict which patients will de ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Open Source System for Audio Processing

    SBC: CREARE LLC            Topic: NIDCD

    This proposal responds to RFA DCin which the NIDCD is seeking to support the development of acoustic signal processing tools that have the potential to accelerate research studies and to facilitate the translation of novel algorithms for hearing aidsApproximatelyof American adults report some degree of hearing troubleandof Americans agedand over experience bilateral hearing lossHLThehearing aid in ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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