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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Bio-mathematical Models of Aggregated Tissues & Organ Properties

    SBC: Corvid Innovation LLC            Topic: DHP16A001

    Realistic surgical simulation requires a combination of representative tissue geometry, accurate tissue material properties and lifelike tool-tissue interaction forces. Recent advances in computational power and imaging modalities have provided the capability to represent the anatomical details required for surgical training; however, the mathematical models which govern the underlying tissue pro ...

    STTR Phase II 2017 Department of DefenseDefense Health Program
  3. Development of Technologies that Address the Complex Architecture of the Face During the Treatment of Severe Facial Burn Injury

    SBC: Keranetics, LLC            Topic: DHP13016

    Burn injuries to theface present a number of functional and psychological challenges that arisefrom scarring and contracture. Thus, amajor goal of burn and trauma surgeons is to prevent scarring and improvegraftingtechnologies that are used on thecomplextopography of the face. The proposed project builds on previous PhaseII SBIR workthat demonstrated thefeasibility of using a keratin-collagen matr ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  4. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  5. Investigation of a sorbent-based potassium adsorber for the treatment of hyperkalemia induced by traumatic injury and acute kidney injury in austere medicine

    SBC: CytoSorbents Medical Inc.            Topic: DHP16010

    Hyperkalemia will clearly continue to be a concern in the treatment of combat casualties. The risk of death from hyperkalemia-induced cardiac arrhythmias is significant in the absence of renal replacement therapy (RRT). Rapid evacuation out of Iraq and Afghanistan ensured that most hyperkalemia occurred further up the evacuation chain, thereby limiting the need for non-RRT hyperkalemia treatment o ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  6. Model-Based Design of Test Systems for Chemical Protective Clothing

    SBC: CREARE LLC            Topic: CBD02202

    The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  7. Mycotoxin Adsorption with Hemocompatible Porous Polymer Beads

    SBC: CytoSorbents Medical Inc.            Topic: CBD152003

    Certain species of fungi produce mycotoxins, which can cause acute toxicity and even death in human that either have been, or potentiallycould be, used by bioterroists as weapons of mass destruction. Aflatoxin and trichothecene T-2 toxin are two mycotoxins that are of particularconcern as potential biological weapons due to their toxicity, environmental stability, easy accessibility, historical pr ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  8. Signal Processing for Layered Sensing

    SBC: Vadum, Inc.            Topic: CBD152006

    Vadum will develop Chemical, Heterogeneous sensor fusion Incident awareness Module (CHIME)asoftware module that will ingest data from a large number of asynchronous, heterogeneous and multi-tiered sensors to automate the process of estimating the source attributes of a chemical or biological release. CHIME generates estimates from a continuous stream of raw sensor data with successive estimates al ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  9. Use of Highly Porous Polymer Beads to Remove Anti-A and Anti-B Antibodies from Plasma for Transfusion

    SBC: CytoSorbents Medical Inc.            Topic: DHP15B001

    Plasma from AB donors is considered universal as it can be transfused regardless of recipient blood type and is frequently used to rapidly resuscitate massively bleeding hospital trauma patients and warfighters with combat casualties. However supplies can be rapidly depleted as AB donors make up only 4% of the population. Therefore robust a technology to cost-effectively generate universal plasma ...

    STTR Phase II 2017 Department of DefenseDefense Health Program
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