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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Zymeron Corporation            Topic: CBD161003

    The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD Research Corporation            Topic: CBD152003

    Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  4. Hermetic Seals for Chemical/Biological Protective Garments

    SBC: CREARE LLC            Topic: CBD13109

    Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare is developing hermetic garment closure systems that seal macroscopic and microscopic gaps at interfaces and closures and provide high ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  6. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  7. Model-Based Design of Test Systems for Chemical Protective Clothing

    SBC: CREARE LLC            Topic: CBD02202

    The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: iXpressGenes, Inc.            Topic: CBD152004

    This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  9. Signal Processing for Layered Sensing

    SBC: Vadum, Inc.            Topic: CBD152006

    Vadum will develop Chemical, Heterogeneous sensor fusion Incident awareness Module (CHIME)asoftware module that will ingest data from a large number of asynchronous, heterogeneous and multi-tiered sensors to automate the process of estimating the source attributes of a chemical or biological release. CHIME generates estimates from a continuous stream of raw sensor data with successive estimates al ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  10. Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: CFD Research Corporation            Topic: CBD161005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
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