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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Multi-Resolution Representations and Simulation of Large Terrain Models

    SBC: COLLIDE, INC.            Topic: A03207

    We propose to develop multiresolution representations and algorithms for synthetic terrain environments. They will be used for representing large terrain models as well dynamic and atmospheric simulations. Our ultimate goal is to increase the validity of the simulation by incorporating the multiple models at varying resolutions. We will use the OneSAF simulation Product Line Architecture Framework ...

    SBIR Phase II 2005 Department of DefenseArmy
  2. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Automatic Three-Dimensional (3-D) Target Template Generation

    SBC: INTERNATIONAL ASSOCIATION OF VIRTUAL ORGANIZATIONS, INCORPORATED            Topic: N05017

    The US Navy is seeking improved capabilities to quickly and efficiently generate 3-D target templates (or “site models”) to support such operational systems as the Tomahawk Command and Control Systems (TC2S), Distributed Common Ground Station-Navy (DCGS-N), and collateral damage assessment (e.g., CDET and FastCD). There are two parts of interest. The first is to extract valid and reliable 2-D ...

    SBIR Phase II 2005 Department of DefenseNavy
  4. High Efficiency Mission Performance for Underwater Expendable Countermeasure Devices Commonality Applications

    SBC: NEKTON RESEARCH LLC            Topic: N03042

    The proposed Phase II effort will implement design recommendations set forth in the Phase I Final Report. The result will be an efficient, mobile ADC Mk2 (MADC) acoustic countermeasure device. The proposed technology insertion will retain the ADC Mk2 form factor and acoustic package, providing a mobile device that can be deployed with legacy launch systems. MADC will integrate RMP propulsor tec ...

    SBIR Phase II 2005 Department of DefenseNavy
  5. ULTRASENSITIVE METHODS FOR HUMAN BIOMARKER QUANTITATION

    SBC: TRIANGLE LABORATORIES, INC.            Topic: N/A

    Basic research aimed at understanding the complex regulations and interactions lead to various diseases requires novel bioanalytical approaches that allow detailed characterization of the proteome with ultra high-speed and sensitivity so that important regulatory proteins can be effectively studied. For the analysis of complex protein mixtures such as cell lysates, two-dimensional polyacrylamide g ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  6. ULTRA-HIGH RESOLUTION RF PROBE FOR MR HISTOLOGY

    SBC: CREARE LLC            Topic: N/A

    Not Avaialble

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  7. IDENTIFICATION OF NEUROPROTECTIVE APOE-MIMETICS

    SBC: COGNOSCI INC            Topic: N/A

    Not Avaialble

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  8. IMPROVED ASSAYS FOR SPECIFICALLY MEASURING COLLAGENASE-3

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): The matrix metalloproteinases (MMPs) are associated with, and may be predictors of diseases such as osteoarthritis (OA), rheumatoid arthritis (RA), and cancer. In Phase I, we discovered novel and selective substrates for the MMP collagenase 3, an enzyme implicated in OA and cancer progression. Substrates were obtained by modifying sequence data gained from sub ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  9. Synthesis and Evaluation of a Novel Anti-HIV Agent

    SBC: Kucera Pharmaceutical Company            Topic: N/A

    The long-term goal of this research is to develop a drug that is safe and effective against drug-resistant human immunodeficiency virus (HIV) infection. Several challenges confront current anti-HIV chemotherapy. The frequency of drug-resistant and multidrug-resistant HIV-1 is increasing. Toxicities associated with current HIV medications often result in the discontinuation of these therapies. Phys ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. ECHINACEA: STANDARDIZED PRODUCT & SUPPLY PROVISION

    SBC: Gaia Herbs, Inc.            Topic: N/A

    SBIR phase I will lay the groundwork for standardized Echinacea production in Phase II. The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field conditions, and morphologic, organoleptic, chromosome/DNA, and microscopic characteristics wi ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
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