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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYNucleosomesNucsare the repeating units of chromatinmade up of DNA wrapped around a histone octamerChanges in chromatin structurefunction can dramatically impact downstream gene expression and cellular physiologydriving oncogenic reprogramming and cancer progressionThis epigenetic regulation of chromatin is controlled by two major modificationshistone post translational modifications ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A CLEAN HELIUM COMPRESSOR/EXPANDER FOR LONG LIFE CRYOGENIC SERVICE

    SBC: CREARE LLC            Topic: N/A

    CRYOGENIC HELIUM REFRIGERATORS AND LIQUIFIERS CONVENTIONALLYEMPLOY OIL LUBRICATED POSITIVE DISPLACEMENT COMPRESSORS AT THE WARM END AND FREQUENTLY USE PISTON TYPE EXPANSION ENGINES AT THE COLD END. THESE SYSTEMS REQUIRE EXTENSIVE AND VIGILANT MAINTENANCE TO CONTROL CONTAMINATION FROM LUBRICATING OIL AND ITS VOLATILE COMPONENTS MIGRATING TO THE COLD END. HENCE THE NEED FOR LOW MAINTENANCE COMPRESSO ...

    SBIR Phase II 1987 Department of Energy
  3. A Compact and Agile Fixed-Wing UAS for VTOL Shipboard Operations

    SBC: CREARE LLC            Topic: 832

    TECHNICAL ABSTRACT: Commercially available unmanned aircraft systems (UASs) are not well designed to meet requirements for many atmospheric measurement applications, including deployment from ships, long endurance, and low cost. Existing multi-rotor systems suffer from limited payload and endurance. Existing fixed wing systems offer improved endurance and payload, but require significant support h ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  4. ACTIVELY CONTROLLED GAS BEARINGS

    SBC: Burton Technologies Inc            Topic: N/A

    RESEARCH AND DEVELOPMENT WILL BE CARRIED OUT TO PROVIDE PROTOTYPE, ACTIVELY CONTROLLED GAS BEARINGS FOR PRECISION MOVEMENT IN INSTRUMENTS AND MACHINE TOOLS. THIS WILL DRAW UPON PRELIMINARY WORK ON (1) FABRICATION, (2) DYNAMIC ANALYSIS OF THE BEARING AND SUPPORTED MASS, (3) PIEZOELECTRIC VALVING AND PIEZOELECTRIC DISPLACEMENT OF THE BEARING SURFACE, AND (4) THE ADAPTATION OF A MICROPROCESSOR TO SER ...

    SBIR Phase II 1987 National Science Foundation
  5. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA

    SBC: THREE C INSTITUTE FOR SOCIAL DEVELOPMT            Topic: N/A

    Location 1903 N HARRISON AVE, STE 101 CARY, NC 27513 United States N44MH0664102C $365 147.00 2 005 ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA Department of Health and Human Services SBIR PHS2006-1 THREE C INSTITUTE FOR SOCIAL DEVELOPMT Phase ...

    SBIR Phase II 2005 Department of Health and Human Services
  7. Adaptive Hyperspectral Sensor for Battlefield Combustibles

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: AF04207

    The objective of this program is to develop a wide field of view spectral imaging sensor to support theater surveillance and intelligence. The AHS operates in the Mid Wave Infrared (MWIR) band and provides day/night spectral target cueing, geolocation and identification of hot battlefield threats. Currently deployed EO sensors can measure broadband MWIR signals, but are incapable of providing adva ...

    SBIR Phase II 2005 Department of DefenseAir Force
  8. A DNA Taggant Watermarking System

    SBC: EAGLE EYE, INC.            Topic: AF04124

    Taggants are small objects used to label things or people that need to be traced. Synthetic DNA Taggants are ideal for this, since very small amounts can be detected if the sequence is known, and can be disguised by natural DNA in the environment. Known protocols for DNA amplification (e.g. PCR) allow for very sensitive DNA detection, but suffer from disadvantages: the apparatus is not very portab ...

    SBIR Phase II 2005 Department of DefenseAir Force
  9. Advanced Helmet for Maintainer Head and Hearing Protection

    SBC: CREARE LLC            Topic: N04255

    Improved head and hearing protection is required for aircraft maintainers working on a carrier flight deck during launch and recovery operations. The current head protection is inadequate in many aspects including impact protection, hearing protection, cleaning, comfort, and compatibility with night vision goggles (NVGs) and with chemical, biological, and radiological (CBR) equipment. Creare pro ...

    SBIR Phase II 2005 Department of DefenseNavy
  10. Advanced Helmet for Maintainer Head and Hearing Protection

    SBC: CREARE LLC            Topic: N04255

    Improved head and hearing protection is required for aircraft maintainers working on a carrier flight deck during launch and recovery operations. Legacy Flight Deck Cranials are inadequate in many aspects including hearing protection and impact protection. In previous work, Creare has developed a Flight Deck Cranial (FDC) that offers unparalleled hearing protection and industrial standard head pro ...

    SBIR Phase II 2018 Department of DefenseNavy
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