Award Data

Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram - negative bacteria and the causative agents of melioidosis and glanders, respectively. These infections, which occur in humans and other animals, are endemic is wide regions of the developing world. This Phase II SBIR project will build on the success of our Phase I work, which established methods for generating monoclon ...

NON-TECHNICAL SUMMARY: The small intestine of the newly hatched chick and is immature and undergoes significant morphological, biochemical and physiological changes during the first 10 days post hatch. After this initial period, the gastrointestinal tract (GIT) of the young monogastric animals becomes more capable of digesting and utilizing more nutrients. Chicks and poults during the first few da ...

NON-TECHNICAL SUMMARY: Economic impacts due to coldwater disease (CWD) have dramatically increased in recent years at public and private aquaculture facilities and CWD is the number one disese problem in the commercial rainbow trout industry in Idaho. In the United States, antibiotics available for the therapeutic treatment of fish with this disease are very limited and not expected to increase. V ...

THE U.S. POULTRY INDUSTRY ADMINISTERS ABOUT 21 BILLION DOSE UNITS OF VACCINES YEARLY. THESE VACCINATIONS ARE GIVEN TO TO DAY-OLD BIRDS FOR SEVERAL VIRAL AND BACTERIAL DISEASES, AND SUBSEQUENT VACCINATIONS TO GROWING AND ADULT CHICKENS ANAND TURKEYS. ADDITIONALLY, 170 MILLION TURKEY EMBRYOS R RECEIVE ANTIBIOTIC TREATMENT. THE WORLDWIDE POULTRY DRUG VACCINE MARKET REPRESENTS OVER $500 MILLION PR YEA ...

NON-TECHNICAL SUMMARY: The seafood industry is well aware of the need for maintaining product quality. It has traditionally relied on subjective sensory analysis through human sniff tests for the assessment of seafood freshness. However, experts are costly and too few in number. Alternative objective tests are expensive, complicated, time consuming, require toxic chemicals and destructive sampling ...

OmniSite proposes to continue Phase I effort to develop aptamer-based assays to anthrax spores and SEB for detection instruments based on ECL, FP, and FRET formats. OmniSite will compare the different assay formats to determine which of thesedemonstrates the most sensitivity and specificity, as well as being robust, cost effective, and facile. Performance characteristics of the most sensitive ...

The lateral flow (LF) or immunochromatographic (IC) test strip is a staple test format in the food safety testing arsenal. However, the sensitivity of LF assays is limited partly due to antibody affinity and partly due to the visual detection limit of colloidal gold or colored latex particles. Operational Technologies Corporation (OpTech) has developed hundreds of high affinity candidate DNA aptam ...