Award Data

Outdoor acoustics simulation plays a vital role in several army and defense-related applications, such as minimizing the noise profile of reconnaissance vehicles to avoid counter-detection, optimizing sensors and systems for tactical advantage, and pinpointing the origin of gunshots using their acoustic signatures. Outdoor acoustics prediction technology is needed to efficiently model large, compl ...

EE Boost Inc. proposes to develop a new, fast and accurate hybrid wave-based method for acoustic simulation in large and complex environments. The hybrid method combines two efficient methods: the pseudo-spectral time-domain (PSTD) method and the enlarged cell technique (ECT). The PSTD method is extremely fast and accurate in computing fields in large cuboids without internal boundaries and interf ...

The chloroperoxidase enzyme from the filamentous fungus Caldariomyces fumago has applications in industrial chemical synthesis and the detection and inactivation of chemical warfare agents. Chloroperoxidase is capable of regio- and enantioselective oxygenations and halogenations of organic substrates. When performed chemically, these reactions typically require aggressive reagents and reaction c ...

The ability to direct the wound pathways following injury could provide a critical path in wound care at crucial times during the progression of healing. A promising field of study in wound healing is epigenetics; alterations in gene expression caused by mechanisms other than changes in DNA sequence. Identification of epigenetic factors and their manipulation may result in the development of nov ...

Applied Quantum Technologies proposes the development of a snapshot Raman spectral imager for chemical imaging applications with a 1-5 meter standoff. Standoff chemical imaging methods are typically point-based, making scan times impractical for situations where a wide area needs to be surveyed. The high spectral resolution needed to take advantage of the specificity of Raman spectroscopy limits t ...

The technical objectives of this Phase II project are to identify unique biomarkers and produce molecular, antibody and peptide reagents that are specific for human prostate cancer progenitor stem cells. We propose to utilize the information from the Phase I award and subsequent research to develop assay reagents that would be used to develop a blood-based assay specific for circulating prostate c ...

U.S. Military operations have come to depend more and more on unmanned vehicles (unmanned undersea vehicles UUVs and unmanned air vehicles UAVs) to carry out numerous missions. However, the transit distance for many of these missions is often well limited by the energy storage capacity of their power systems. Fuel cell, particularly SOFC that can be fed directly with reformate, looks promising. Co ...

We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

Physically Unclonable Devices (PUFs) have many applications in security and digital rights management. These devices are used in creation of random number generators used to seed key generation and one-time pad construction for encryption applications. They are also used as a means of uniquely authenticating a piece of hardware or computing device. Given the large applicability of field programmab ...