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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Portable System for Sample Preparation and Differentiation of Pathogens at Strain Level

    SBC: Lynntech Inc.            Topic: CBD04107

    Many believe the greatest threat to our troops and homeland security are attacks using biological weapons. Recent developments of biological warfare agents parallel advances in microbiology, viruses and bacteria can be rendered more lethal through genetic engineering, and many toxins can be mass-produced. However, detecting biological agents is difficult and time consuming because there are thousa ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  3. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  4. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  5. Sensitive Molecular Beacons (MB) Based DNA Microarray

    SBC: BIOMACHINES, INC.            Topic: N/A

    "The DNA microarray is a powerful new technology that can be applied to the detection of biological warfare agents. For the detection of multiple agents, tremendous challenges lie ahead for the DNA microarray technology regarding on sensitivity,selectivity, reliability and consistence. The central theme of this proposal is to apply and optimize a newly developed DNA probe: Molecular beacons (MB) ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  6. Automated Preferential Display for the Analysis of Gene Expression Profiles

    SBC: GENEXPRESS INFORMATICS, INC.            Topic: N/A

    "GeneXpress Informatics, Inc. (GXI) and Dr. James P. Chambers of UTSA propose to develop a revolutionary differential gene display technology, called Preferential Display (PD) which will provide for a simplified, cost-effective method to identify thesegenes for use in discovering gene expression profiles without having any prior knowledge of an organism, tissue or biological samples' genome. The ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  7. New DNA/RNA Sequencer for Rapid Assessment of Exposure to Infectious Agents

    SBC: Lynntech Inc.            Topic: N/A

    "The importance of DNA/RNA-based assays for detection of biological warfare agents, identification of diseases, genome sequencing, and environmental control is enormous and will inevitably increase. The challenge is the development of low cost andportable methods for sequencing DNA and RNA extracted from surfaces and fluids, to recognize exposure to biowarfare agents. All the conventional techn ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  8. New DNA/RNA Sequencer for Rapid Assessment of Exposure to Infectious Agents

    SBC: Lynntech Inc.            Topic: N/A

    "The importance of DNA/RNA-based assays for detection of biological warfare agents, identification of diseases, genome sequencing, and environmental control is enormous and will inevitably increase. The challenge is the development of low cost andportable methods for sequencing DNA and RNA extracted from surfaces and fluids, to recognize exposure to biowarfare agents. All the conventional techn ...

    SBIR Phase II 2002 Department of DefenseOffice for Chemical and Biological Defense
  9. A New High-Level Disinfectant for Medical Instruments

    SBC: RANN RESEARCH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): We have developed a new dialdehyde based cold high-level disinfection/sterilization product for treatment of medical instruments specially heat sensitive fiberoptic endoscopes and have demonstrated that it is 100% e ffective against Mycobacterium tuberculosis in less than 30 minutes at 20 degree Celcius at a concentration of as low as 0.5%. Our formulations ...

    SBIR Phase II 2005 Department of Health and Human ServicesCenters for Disease Control and Prevention
  10. Development of Array-Based Universal Biosensing Devices Based Upon Intelligent Oligonucleotide Probe Sets

    SBC: Vitruvius Biosciences            Topic: N/A

    "The present proposal describes strategies leading to the development of an array-based universal biosensor for detecting and differentiating microbial species, or differentiating at the DNA or RNA level between cell types of the same species. The proposed strategy relies on the differential hybridization of genomic DNA, extrachromosomal DNA, mRNA, or ribosomal RNA from different sources to a comm ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
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