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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  2. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  3. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. NEW BIOLOGICS TO PREVENT SWINE TGE AND PSEUDORABIES

    SBC: Anesta Corpon            Topic: N/A

    AMTRON, INC. WILL UNDERTAKE PRODUCTION AND TESTING LEADING TO U.S. DEPARTMENT OF AGRICULTURE (USDA) APPROVAL OF TWO IM-MUNITY INDUCERS(OFFICIAL NAME DISIGNATED BY USDA) TO PREVENTTHE OCCURENCE OF TRANSMISSIBLE GASTROENTERITIS (TGE) AND PSEUDORABIES VIRUS (PRV) IN NEWBORN PIGS. THE DEVELOPMENT OF IMMUNITY INDUCERS STEMS FROM ADVANCED RESEARCH IN IMMUNO-MODULATORS IN PHASE I, WHICH HAS ENABLED THE C ...

    SBIR Phase II 1987 Department of Health and Human Services
  5. Novel Neurotensin Analogs as Antischizophrenics

    SBC: ARGOLYN BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is the follow-on Phase II SBIR proposal to continue the project Novel Neurotensin Analogs as Antischizophrenics (MH-65099) under PA-06-079 (Pharmacological Agents and Drugs for Mental Disorders). There exists a critical clinical need for the identification and development of novel therapies for psychosis, a major unmet medical need. Low levels of the bra ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. THERMOSYPHON TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. REGENERATIVE TURBINE TARGETRY TO IMPROVE F-18 PET

    SBC: Bruce Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposed work is to reduce the cost of accelerator produced F-18 radiopharmaceuticals used in Positron Emission Tomography (PET), a Medicare-reimbursed nuclear medicine metabolic imaging modality used to diagnose, stage, and restage ten cancer indications. Annual PET scans (350,000+) are rapidly increasing, but CMS reimbursement ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Pancreas Transporter Development and Validation

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of islets of Langerhans for the clinical treatment of Type I diabetes has had a resurgence of interest due to results obtained using the "Edmonton protocol". However, at this time, procurement of donor pancreases for islet isolation and transplantation is in its infancy. Most pancreases at more remote donor sites are not procured due to justifi ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. ENHANCING PEPTIDE DELIVERY TO THE BRAIN

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Traumatic brain injury (TBI) is the leading cause of death and disability in the US with an incidence rate of 1.5 million at cost of $56.3 billion annually. There is no treatment for TBI, and the lack of therapeutic intervention for a public health issue of this magnitude constitutes a healthcare crisis. We have developed COG133, a peptide that is neuroprotecti ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Therapeutic for the Negative Symptoms of Schizophrenia

    SBC: Darpharma, Inc.            Topic: N/A

    DESCRIPTION (PROVIDED BY APPLICANT): Schizophrenia affects roughly 1% of the world's population, with more than two million Americans afflicted in any given year, and an estimated 30-50 million people worldwide. Treatment with available antipsychotic medications often effectively attenuates the positive symptoms of schizophrenia without improvement in the negative symptoms or cognitive deficits. F ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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