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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Design Automation Software for Biomimetic Surface Presentation with DNA Origami

    SBC: PARABON NANOLABS, INC.            Topic: CBD12103

    A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon Parabons existing software for DNA origami design, this project will result in software that can be used to design a ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  2. Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.

    SBC: Qrono, Inc.            Topic: CBD13107

    Elevated levels of human butyrylcholinesterase (hBuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of hBuChE in the plasma for days or weeks. Thus far, plasma-derived hBuChE and PEGylated recombinant forms of BuChE (rBuChE) have been tested in ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  3. Microhydrogel Depot for Sustained Delivery of Prophylactic Bioscavenger

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD13107

    Countering the threat of intoxication by organophosphorus nerve agents is an important mission for homeland security. Currently, the most promising strategy is to bioscavenge the agents using injectable plasma-derived butyrylcholinesterase (BuChE) that has low substrate specificity and may offer a broad spectrum protection against OP agents. Human plasma-derived BuChE at 400mg IV dose is prophylac ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  4. Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments

    SBC: NANOGRIPTECH            Topic: CBD13109

    Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. We demonstrated during Phase I of this project that we can design and fabricate hybrid closure systems which incorporate areas of microfiber adhesive arrays inspired by the foot-hairs found on geckos which ha ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  5. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  6. Novel THz-frequency spectrometers by integrating widely-tunable monochromatic THz sources and detectors, or arrays of emitters and detectors, with pho

    SBC: ArkLight            Topic: CBD04104

    By continuing teaming up with one of the most reputable university teams in THz science and technology, ArkLight proposes to carry out the tasks set for a Phase-II program following our success in Phase I. We are aimed at the further development of novel spectrometers to analyze chemicals in the vapor phase based on accurate measurements of the emission and absorption spectra due to the molecular ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  7. Hermetic Textile Closure Hardware System

    SBC: SIGMA K CORP            Topic: CBD04110

    Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
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