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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerated discovery of methylation targeted therapeutic development

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYNucleosomesNucsare the repeating units of chromatinmade up of DNA wrapped around a histone octamerChanges in chromatin structurefunction can dramatically impact downstream gene expression and cellular physiologydriving oncogenic reprogramming and cancer progressionThis epigenetic regulation of chromatin is controlled by two major modificationshistone post translational modifications ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA

    SBC: THREE C INSTITUTE FOR SOCIAL DEVELOPMT            Topic: N/A

    Location 1903 N HARRISON AVE, STE 101 CARY, NC 27513 United States N44MH0664102C $365 147.00 2 005 ADAPTING EXISTING CURRICULA FOR PROMOTING SOCIAL AND ADA Department of Health and Human Services National Institutes of Health SBIR PHS2006-1 THREE C INSTIT ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Administrative Supplement for the Evaluation of the novel, uni-directional, Pd-103 CivaSheet for Lung Cancer

    SBC: CIVATECH ONCOLOGY INC            Topic: NCI

    Parent Award: R44CA217587 Clinical Evaluation of the novel, Uni-directional Pd-103 CivaSheet for Lung Cancers CivaTech Oncology’s mission is to provide improved radiation therapy directly to localized tumors. The Company has developed a novel, polymer-encapsulated, membrane-like radiation source that emits radiation on only one side of the device – CivaSheet®. This directional source is compa ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Indoor Navigation Aid for Blind and Visually-Impaired Individuals in Unfamiliar Spaces

    SBC: VORTANT TECHNOLOGIES LLC            Topic: N

    Project Summary Abstract Confusionbeing lostand losing track of oneandapos s orientation within large or unfamiliar indoor spacesthese are some of the biggest challenges facing people with visual disabilitiesSince GPS typically doesnandapos t work indoorsand isnandapos t fine grained enough anywayindividuals who cannot readily access visual information are at a significant disadvantageand many bli ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Technology for Administration of the Teen-ASI

    SBC: Health Outcomes Inc            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to conduct a clinical trial using a suite of web-based software products as well as a web portal that will help with standardized assessment, treatment planning, referral, and outcomes tracking for adolescent substance abuse treatment. Products will include the automated Internet version of the Self- Report Teen-Addiction Severity Index (SR-T-ASI Net ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  6. All Stars Technology: Web-Based Program Enhancements

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The success of research-based prevention programs depends on the degree to which they are implemented with fidelity. This Phase II project will enhance All Stars, a drug abuse prevention program, by integrating web-based and multimedia technologies. Enhancements will improve program fidelity by making the program easier to deliver. They will improve effectivene ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. A Low-Cost Platform for Routine High-Accuracy Sizing of Nucleic Acid Samples with 100 bp- 100 Mbp Dynamic Range

    SBC: Genturi Inc.            Topic: 172

    The goal of this project is to develop a microand nanofluidic DNA sizing platform with a sensitivityspeedand dynamic range that is unmatched by current sizing technologiesWe find that fluorescence burst analysis of individual DNA molecules transported through sub micrometer scale channels provides accurate and precise sizing of fragments betweenbp ands of MbpIn this singlemolecule sizing platformu ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. An Integrative Approach to Control Group Creation for Prevention Research

    SBC: PREVENTION STRATEGIES, LLC            Topic: 550

    PROJECT ABSTRACTThe goal of this Phase II SBIR project is to develop a method for creating algorithmically generated control groupsvirtual controlsThese will be composed of synthetic cases that have two characteristicspretest similarity to whatever prevention treatment group may present itself andpatterns of change over time that closely mimic the normal course of alcohol and drug use developmentT ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A novel class of anti-acne therapeutics

    SBC: Verge Therapeutics            Topic: NIAMS

    Acne Vulgaris is a common skin disorder that affectsof the populationtypically teenagers and young adultsOvermillion people in the US are affected by acne generating a $billion market for acne treatmentsof which is derived from prescription medicationsAlthough acne is not a life threatening conditionit still has a high psychosocial impact resulting in depressionanxietyangersuicidal thoughtsphysica ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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