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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.
SBC: Zymeron Corporation Topic: CBD181004
Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
SBC: Zymeron Corporation Topic: CBD161003
The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
SBC: Binergy Scientific Inc. Topic: CBD14101
A chemical threat agent mode of action is often initiated through a selective interaction with a biological molecule or structure. The binding event mimics normal cellular processes, but then overruns natural control mechanisms leading to toxic and lethal effects. The native binding specificity is used to design sensor recognition elements that outperform conventional antibody-based biosensors. Ou ...SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense