Award Data

This proposed project is concerned with the design, fabrication, and demonstration of a new class of plasmonic nanostructures for single molecule surface-enhanced Raman spectroscopy for biological and chemical sensing applications. A complete design of the plasmonic nanostructures with large local field enhancements (E/E0>100) will be formulated, and the fabrication procedures will be developed fo ...

In the past few years, there have been promising demonstrations of new approaches to short-gate (i.e., sub-nanosecond) operation of single-photon avalanche diodes (SPADs) with gating frequencies as high as 2 GHz. However, these demonstrations have had limitations, including operation at just a single fixed frequency, fairly high residual afterpulsing levels, and the lack of industrialization req ...

The chloroperoxidase enzyme from the filamentous fungus Caldariomyces fumago has applications in industrial chemical synthesis and the detection and inactivation of chemical warfare agents. Chloroperoxidase is capable of regio- and enantioselective oxygenations and halogenations of organic substrates. When performed chemically, these reactions typically require aggressive reagents and reaction c ...

In this STTR program, Structured Materials Industries, Inc. (SMI) and partners will develop high efficiency, switchable RF filters. The technical approach is based on thin films of paraelectric BaxSr1-xTiO3 and SrTiO3, which can show piezoelectric behavior under an applied DC bias. When integrated into resonator structures, these materials can act as both an RF filter and an RF switch. Combinin ...

The ability to direct the wound pathways following injury could provide a critical path in wound care at crucial times during the progression of healing. A promising field of study in wound healing is epigenetics; alterations in gene expression caused by mechanisms other than changes in DNA sequence. Identification of epigenetic factors and their manipulation may result in the development of nov ...

The technical objectives of this Phase II project are to identify unique biomarkers and produce molecular, antibody and peptide reagents that are specific for human prostate cancer progenitor stem cells. We propose to utilize the information from the Phase I award and subsequent research to develop assay reagents that would be used to develop a blood-based assay specific for circulating prostate c ...

U.S. Military operations have come to depend more and more on unmanned vehicles (unmanned undersea vehicles UUVs and unmanned air vehicles UAVs) to carry out numerous missions. However, the transit distance for many of these missions is often well limited by the energy storage capacity of their power systems. Fuel cell, particularly SOFC that can be fed directly with reformate, looks promising. Co ...

Physically Unclonable Devices (PUFs) have many applications in security and digital rights management. These devices are used in creation of random number generators used to seed key generation and one-time pad construction for encryption applications. They are also used as a means of uniquely authenticating a piece of hardware or computing device. Given the large applicability of field programmab ...

The Intelligence Community and recent trend analysis suggests that future terrorism will expand the use of IED, VBIED"s and Person Borne Suicide Vests. Current Explosive Ordnance Disposal (EOD) technology uses Single Shot Disruptors for disarming these threats whenever possible. Recent development has mounted these Disruptors onto the Man Transportable Robot System (MTRS). These Disruptors are Sin ...

The objective of this SBIR Phase I proposal is to develop novel lightweight combustible small arms ammunitions to replace brass cased ammunitions with improved burning efficiency and mechanical properties, alleviated weight and superior ballistic performance. In order to deliver a cost-effective and highly performed combustible cartridge that meets all the requirements and is suitable for mass pro ...