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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of Selective Inhibitors of NaV as Therapeutics for Pain

    SBC: SITEONE THERAPEUTICS, INC.            Topic: 108

    PROJECT SUMMARY This program aims to develop a novel non opioid therapeutic for the treatment of pain that targets a subtype of the human voltage gated Na ion channel NaV Preliminary data indicate that SiteOneandapos s lead drug candidates may be more effective than opioids for treating certain types of pain and lack the side effects associated with opioid analgesics which include nausea ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Personal Neutron Detector Based on Cadmium Telluride

    SBC: LITHIUM INNOVATIONS COMPANY, LLC            Topic: HSB0151009

    In this Phase II SBIR project, Lithium Innovations, in partnership with Lucintech Inc, will build on the success of its innovative thin-film neutron detector developed and tested in Phase I. The detector is based on the use of a metallic lithium-6 sensitizer layer paired with a thin-film CdS/CdTe heterojunction to detect the alpha and triton charged particles produced by the n + Li-6 reaction. Th ...

    SBIR Phase II 2016 Department of Homeland Security
  3. Quantitative PCR Platform for The Assessment of Alcohol Consumption

    SBC: BEHAVIORAL DIAGNOSTICS, INC.            Topic: NIAAA

    DESCRIPTION provided by applicant Heavy alcohol use is common and presents a major social economic challenge Although chronic use of small amounts of alcohol is not always harmful heavier use andgt drinks day is generally harmful and frequently leads to alcoholism or as it is termed in ICD Alcohol Use Disorder AUD AUD affects of the U S population and causes over $ billio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Safe and effective anti CD antibodies for therapeutic intervention

    SBC: Immunext, Inc.            Topic: R

    Abstract CD CD L is a key target for immunomodulation due to its central role in controlling the activation of the immune system This well studied immune switch has been the focus of extensive drug development for over two decades The validation of this drug target consists of reproducible and robust data using rodent and NHP models of chronic inflammation autoimmune disease and organ ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Regulatory Approval of the OLFACT Test Battery

    SBC: OSMIC ENTERPRISES, INC.            Topic: NIA

    DESCRIPTION provided by applicant Although there are numerous scientific studies in the literature that show impairments in olfaction often occur early in the onset of Alzheimerandapos s Disease AD there is still concern pertaining to the specificity of measures of olfactory dysfunction when used as a predictor of AD For this and other reasons there is no test based upon measures of olfact ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Electrical stimulation to reduce pain and improve function after knee replacement

    SBC: SPR THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION provided by applicant The goal of this project is to evaluate the feasibility Phase I and demonstrate the safety and effectiveness Phase II of a novel peripheral nerve stimulation therapy to treat pain and enable early rehabilitation after total knee arthroplasty i replacement resulting in improved function independence and quality of life Total knee arthroplasty is a s ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Validation of a rapid point-of-care breath test for breast cancer

    SBC: MENSSANA RESEARCH INC            Topic: NCI

    DESCRIPTIONprovided by applicantThe clinical problemBreast cancer is the commonest cancer in womenin whom it is second only to lung cancer as a cause of cancer deathMammography is the mainstay of screening for breast cancerthough its value is limited by its large number of false positive and false negative findingsA new solution the problemThe combination of two diagnostic tests with different bio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Large-Area Plasma Panel Detectors for Particle Beam Radiation Therapy

    SBC: Integrated Sensors, LLC            Topic: NCI

    DESCRIPTIONprovided by applicantA joint DOE NCI workshop on ion beam therapyJanuaryBethesdaMDidentified an ambitious set of technology developments needed to support a world class treatment program for ion beam therapyOne important requirement is the ability to provide detectors that afford single particle registration at high data rates with hgh degree of uniformity and minimal interference with ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Novel Fast GPU Monte Carlo and Active Photonics Simulation Software for Predicting PDT Efficacy

    SBC: SIMPHOTEK, INC.            Topic: 102

    DESCRIPTION provided by applicant Photodynamic therapy PDT provides for standalone or intraoperative cancer treatment PDT provides a means to treat superficial and or residual disease while minimizing damage to underlying tissues and does not exhibit cumulative cell toxicities distinguishing it from radiation therapy As compared to radiotherapy treatment planning in PDT is often approa ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Compact super directional microphone array to improve hearing in background noise

    SBC: MH ACOUSTICS LLC            Topic: NIDCD

    Project Summary Abstract Hearing in noise is one of the major problems reported by hearing impaired individuals wearing hearing aids when trying to participate in conversations with background noise In a typical restaurant or similar noisy situation background noise significantly reduces the intelligibility of speech for hearing impaired listeners The objective of this project is to build a c ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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