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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Peptide inhbitors of influenza entry-FAST TRACK

    SBC: Autoimmune Technologies, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Between 10% and 20% of the United State population suffer from seasonal influenza each year. While most individuals recover from influenza in one to two weeks, the very young, the elderly and persons with chronic medical conditions can develop post-flu pneumonia and other lethal complications. The causative agent of influenza is influenza virus, a myxovirus tha ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Multivalent Vaccines Against Yellow Fever and Arena Viruses

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: NIAID

    DESCRIPTION (provided by applicant): Indigenous population, travelers and troops present in Africa and South America are clearly at risk of exposure to several arenaviruses. Several human pathogenic arenaviruses, e.g., Lassa and Junin viruses, are listed on the NIAID's Priority Pathogens and CDC's Bioterrorism Agents Lists and can cause a deadly hemorrhagic fever. No effective and safe vaccine is ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Camptothecin Analogs for Cancer Therapy

    SBC: DEKK-TEC INC            Topic: NCI

    DESCRIPTION (provided by applicant): 7-Butyl-10-aminocamptothecin (BACPT), as a water-soluble dipeptide pro-drug - BACPTDP, is a novel camptothecin analog that has increased activity in hypoxic/acidic tumor tissues, characteristic of fast growing cancers that characteristically have deficient vasculature and outgrow their blood supply. Both in vitro and in vivo studies support the potential useful ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Multi-Spectral Combat ID Beacon

    SBC: Diffraction, Ltd            Topic: SOCOM10008

    Diffraction LTD will develop a multi-spectral battery powered combat ID beacon. Key emitter technologies will include vacuum encapsulated photonic crystals in the MWIR and LWIR spectral bands. In Phase 1, a complete optical, electrical, and mechanical design of the beacon will be produced. A model taking into account emitter characteristics, atmospheric transmission, ambient lighting, and vario ...

    SBIR Phase I 2010 Department of DefenseSpecial Operations Command
  5. Development of a Humanized Pig Model of Cystic Fibrosis

    SBC: EXEMPLAR GENETICS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a chloride channel that regulates ion flow across epithelial cell membranes. Most CF patients have a mutation that deletes phenylalanine 508 (?F508) and prevents CFTR from being properly processed and delivered to cell membra ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Porcine Model of Atherosclerosis

    SBC: EXEMPLAR GENETICS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Atherosclerosis is the primary cause of cardiovascular disease, which is the most common cause of death in the United States. Atherosclerosis is characterized by the accumulation of lipids, cholesterol, calcium deposits, and cellular debris in vessel walls, and results in plaque formation, arterial obstruction, and diminished blood flow to organs. These plaqu ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Optimization of U1 Adaptor Technology

    SBC: INTEGRATED DNA TECHNOLOGIES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Our understanding of complex biological phenomena and disease progression has led to the realization that changes in the expression of genes underlie many of these processes. Developing reagents that can selectively alter the expression level of any desired gene has been a goal of both scientists and clinicians for years. Historically, the most common approach ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Software to Enrich the Noun Lexicons and Lexical Learning of Children with Autism

    SBC: LAUREATE LEARNING SYSTEMS, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): The objective of this project is to develop a curriculum and prototype software for a research-based vocabulary development program featuring a combined lexical-cognitive approach to noun acquisition. The target population for the curriculum will be children ages 3;0 to 12;0 with Autism Spectrum Disorders (ASD) as well as a broad range of other children with la ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Nutritional Intervention for Age-Related Muscular Function and Strength Losses

    SBC: MTI Biotech Incorporated            Topic: NIA

    DESCRIPTION (provided by applicant): Sarcopenia, defined as age related loss of muscle mass and muscle function and strength, is very prevalent among the elderly. Sarcopenia is one of the largest public health problems facing a rapidly increasing, aging population in the United States and leads to increased incidence of falls, fractures and associated morbidities. Previous observations from our la ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Automated Neuron Tracing and 3D Reconstruction Software

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): We propose to develop NeuroAutomatica, an innovative, automated neuron reconstruction software platform that provides analysis tools for automated quantitative analysis of neuronal structure. The software will provide multi-scalar information about multiple individual neurons in close proximity, including dendritic spines. Providing this innovative functionalit ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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