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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: Low cost portable system for the rapid detection and drug resistance profiling of Tuberculosis

    SBC: Impedx Diagnostics            Topic: BM

    This Phase I SBIR project is directed at developing a portable, sensitive, and affordable device to detect M. tuberculosis (Mtb) in sputum samples and simultaneously determine the multidrug resistance profile of the pathogen, all within 3 days of sputum collection (It takes more than 6 weeks using current technology). By significantly reducing the time to detect viable Mtb and obtain its drug resi ...

    SBIR Phase I 2017 National Science Foundation
  2. Aerosolized platinum nanoparticle chemotherapy for lung cancer

    SBC: NANOPHARM, LLC            Topic: 102

    Significance Lung cancer is the leading cause of cancer deaths with over new diagnoses annually Survival rate of lung cancer patients is correlated with the extent of lymph node metastasis Standard care includes chemotherapy radiation and or surgery Cisplatin is a first line chemotherapy for lung cancer but systemic intravenous IV delivery is confounded by various toxicities rena ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. ADVANCED MANUFACTURING OF MICRO POCKET FISSION DETECTOR (MPFD)

    SBC: Radiation Detection Technologies Inc.            Topic: 29a

    A need exists for advanced instrumentation neutron-flux mapping with in the reactor-core for the Transient REActor Test (TREAT) facility and Advanced Test Reactor (ATR) experiments supporting advanced nuclear material testing. In addition, many U.S. research reactors and industrial power nuclear-reactors would benefit from in-core neutron-flux monitoring. Here it is proposed to research advanced M ...

    SBIR Phase I 2017 Department of Energy
  4. Wide-Bandgap Microstructured Semiconductor Neutron Detector

    SBC: Radiation Detection Technologies Inc.            Topic: 26b

    There is a need for high-efficiency, radiation hard, high-temperature neutron detectors at nuclear reactor and nuclear physics facilities. Nuclear physic experiments require neutron detectors that are robust, compact, low-power, and have high-sensitivity, while stably operating in harsh environments, e.g., high-temperature and high radiation-dose. Wide-bandgap semiconductors will tolerate such env ...

    SBIR Phase I 2017 Department of Energy
  5. Precision Microspheres for Transtympanic Delivery of Ganciclovir for CMV Infection

    SBC: ORBIS BIOSCIENCES, INC.            Topic: Y

    PROJECT SUMMARY Current approaches to treat sensorineural hearing loss SNHL in newborns suffering from congenital cytomegalovirus CMV infection rely on off label systemic antiviral therapy requiring high dose long duration treatment with demonstrated hematologic toxicity carcinogenicity and teratogenicity Furthermore it is unknown whether systemic delivery of antivirals maintain inner e ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Low-cost portable system for the rapid detection and drug resistance profiling of Tuberculosis in low resource environments.

    SBC: IMPEDX DIAGNOSTICS, INC.            Topic: NICHD

    Tuberculosis TB is one of the major public health challenges in the world today with an estimated million deaths in More alarmingly the incidence of multi drug resistant MDR TB is rapidly increasing especially in low resource environments The goal of this project is to develop an inexpensive portable system and method using which it will be possible to both detect the presence of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a GABA Enzyme for Biosensor Applications

    SBC: PINNACLE TECHNOLOGY, INC            Topic: 101

    Abstract As the most important inhibitory neurotransmitter in the brain a detailed understanding of the implications of gamma aminobutyric acid GABA release remains elusive The measurement of GABA concentrations is a difficult process Microdialysis is the current standard for GABA sampling in the brains of freely moving animals but suffers from low temporal resolution and the need for labor ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Collision-Avoidance Radar for Small UAS

    SBC: UAVradars, LLC            Topic: A2.02

    In the near future unmanned aircraft systems (UAS) will be utilized for many societal and commercial applications. However, the hurdle of operation safety in the form of avoiding airborne collisions must first be overcome. UAVradars LLC is proposing a small, lightweight, and low-power radar system designed specifically to give small UAS (< 55 lbs) airborne collision-avoidance sensory capability. ...

    SBIR Phase II 2016 National Aeronautics and Space Administration
  9. Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates

    SBC: EVOKE MEDICAL, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The objective of this Phase I STTR research is to develop and test osteoinductive lumbar spinal fusion implant prototypes made using materials technology developments discovered by the PI at the University of Kansas In preliminary work lower impedance piezoelectric composite materials that generate power for direct current DC electrical stimulation applica ...

    STTR Phase I 2016 Department of Health and Human Services
  10. Development of a GABA Enzyme for Biosensor and Point-of-Care Applications

    SBC: PINNACLE TECHNOLOGY, INC            Topic: 101

    DESCRIPTION provided by applicant As the most important inhibitory neurotransmitter in the brain a detailed understanding of the implications of gamma aminobutyric acid GABA release remains elusive The measurement of GABA concentrations is a difficult process Microdialysis is the current standard for GABA sampling in the brains of freely moving animals but suffers from low temporal resolu ...

    SBIR Phase I 2016 Department of Health and Human Services

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