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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: Low cost portable system for the rapid detection and drug resistance profiling of Tuberculosis

    SBC: Impedx Diagnostics Inc.            Topic: BM

    This Phase I SBIR project is directed at developing a portable, sensitive, and affordable device to detect M. tuberculosis (Mtb) in sputum samples and simultaneously determine the multidrug resistance profile of the pathogen, all within 3 days of sputum collection (It takes more than 6 weeks using current technology). By significantly reducing the time to detect viable Mtb and obtain its drug resi ...

    SBIR Phase I 2017 National Science Foundation
  2. Aerosolized platinum nanoparticle chemotherapy for lung cancer

    SBC: HYLAPHARM LLC            Topic: 102

    Significance Lung cancer is the leading cause of cancer deaths with over new diagnoses annually Survival rate of lung cancer patients is correlated with the extent of lymph node metastasis Standard care includes chemotherapy radiation and or surgery Cisplatin is a first line chemotherapy for lung cancer but systemic intravenous IV delivery is confounded by various toxicities rena ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Wide-Bandgap Microstructured Semiconductor Neutron Detector

    SBC: Radiation Detection Technologies, Inc.            Topic: 26b

    There is a need for high-efficiency, radiation hard, high-temperature neutron detectors at nuclear reactor and nuclear physics facilities. Nuclear physic experiments require neutron detectors that are robust, compact, low-power, and have high-sensitivity, while stably operating in harsh environments, e.g., high-temperature and high radiation-dose. Wide-bandgap semiconductors will tolerate such env ...

    SBIR Phase I 2017 Department of Energy
  4. ADVANCED MANUFACTURING OF MICRO POCKET FISSION DETECTOR (MPFD)

    SBC: Radiation Detection Technologies, Inc.            Topic: 29a

    A need exists for advanced instrumentation neutron-flux mapping with in the reactor-core for the Transient REActor Test (TREAT) facility and Advanced Test Reactor (ATR) experiments supporting advanced nuclear material testing. In addition, many U.S. research reactors and industrial power nuclear-reactors would benefit from in-core neutron-flux monitoring. Here it is proposed to research advanced M ...

    SBIR Phase I 2017 Department of Energy
  5. Precision Microspheres for Transtympanic Delivery of Ganciclovir for CMV Infection

    SBC: ORBIS BIOSCIENCES, INC.            Topic: Y

    PROJECT SUMMARY Current approaches to treat sensorineural hearing loss SNHL in newborns suffering from congenital cytomegalovirus CMV infection rely on off label systemic antiviral therapy requiring high dose long duration treatment with demonstrated hematologic toxicity carcinogenicity and teratogenicity Furthermore it is unknown whether systemic delivery of antivirals maintain inner e ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a GABA Enzyme for Biosensor Applications

    SBC: Pinnacle Technology, Inc.            Topic: 101

    Abstract As the most important inhibitory neurotransmitter in the brain a detailed understanding of the implications of gamma aminobutyric acid GABA release remains elusive The measurement of GABA concentrations is a difficult process Microdialysis is the current standard for GABA sampling in the brains of freely moving animals but suffers from low temporal resolution and the need for labor ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Low cost portable system for the rapid detection and drug resistance profiling of Tuberculosis in low resource environments

    SBC: Impedx Diagnostics Inc.            Topic: NICHD

    Tuberculosis TB is one of the major public health challenges in the world today with an estimated million deaths in More alarmingly the incidence of multi drug resistant MDR TB is rapidly increasing especially in low resource environments The goal of this project is to develop an inexpensive portable system and method using which it will be possible to both detect the presence of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Broadcast Seeder Implement for Seeding Cover Crops in Standing Cash Crops

    SBC: Mechanized Design            Topic: 8.13

    The current issue this research addresses is the lack of an affordable method for small and midsize farms to plant cover crops into standing cash crops. Cover crops are crops planted either into standing cash crops (such as corn or soybeans) or in between cash crop seasons that are planted for reasons other than harvesting for grain. Using cover crops can help reduce the amount of irrigation and c ...

    SBIR Phase I 2017 Department of Agriculture
  9. GENERATING SYNERGY BETWEEN PROTEIN AND NON PROTEIN MACROMOLECULAR ADJUVANTS

    SBC: Hafion LLC            Topic: NIAID

    The Contractor will examine the additive and potentially synergistic activities of two potential adjuvants as a combined adjuvant low molecular weight hyaluronan Haf and the A subunit of the Escherichia coli heat labile enterotoxin LTA The adjuvants will be examined in the context of protection against Bordetella pertussis the causative agent of pertussis whooping cough

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. ExtruMach-Mill

    SBC: Fairmount Technologies LLC            Topic: DLA152-001

    Fairmount Technologies (FT) has demonstrated that ExtruMach is a disruptive technology for drilling curved extrusions and proposes to further develop this during Phase II for milling extrusions. ExtruMach-PoCM (proof of concept machine) is a flow-type multi-axis CNC machine with a small footprint, which is more capable than existing machines in that it has no limit on the length of parts it can ha ...

    SBIR Phase II 2017 Department of DefenseDefense Logistics Agency

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