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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: Commercial Scale Separation Modules with Integrated Sensors for Cost-Effective, Real-time Detection of Membrane Fouling

    SBC: Racing Testing LLC            Topic: CT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to significantly increase the efficiency and reduce operating costs for water produced by membrane-based desalination. Water scarcity is an increasingly important global-scale issue that has significant negative impacts on health, security and economies. Recent forecasts show a dramatic increase in ...

    SBIR Phase I 2018 National Science Foundation
  2. SBIR Phase I: A Chemoselective Microreactor for Breath Analysis


    This SBIR phase I project seeks to address the critical need for lung cancer diagnosis at an early stage. North America has the highest age-standardized incidence of lung cancer in the world. An estimated 224,390 new cases of lung cancer will be diagnosed this year and 158,080 deaths are predicted to occur due to lung cancer in 2016. The five-year survival rate for lung cancer patients is much low ...

    SBIR Phase I 2017 National Science Foundation
  3. Vagus Nerve Stimulation Treatment for Asthmatic Bronchoconstriction


    Project Summary The Specific Aim of this proposal is to test the feasibility of using vagus nerve stimulation VNS for treating asthma related airway constriction that is refractory to current treatments There are approximately million people with asthma in the US About percent of these asthma sufferers experience early and late phase severe asthmatic bronchoconstriction that is refract ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Harvesting specific plant metabolites from hairy root cultures using magnetized nanoparticles

    SBC: NAPROGENIX, INC.            Topic: R

    Abstract Plant cell cultures are becoming a commercially valuable source of pharmaceuticals particularly those that are too complex for economical chemical synthesis For example Phyton Biotech in Germany has achieved great commercial success by generating taxoids for Paclitaxel production in sterile plant cell bioreactors However the efficiency of these systems is limited by the loss in via ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Experimental Gonococcal Vaccine

    SBC: THERAPYX, INC.            Topic: NIAID

    ABSTRACT Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and it can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent findings have revealed that ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Phase II Feasibility assessment of a novel tool for mosquito vector control Auto Dissemination Augmented by Males ADAM

    SBC: MOSQUITOMATE, INC.            Topic: R

    Project summary abstract Mosquito control remains the primary tool for combating many mosquito vectored diseases such as Dengue Chikungunya Zika and West Nile because no approved vaccine therapeutant or prophylaxis is currently available for use Key deficiencies of existing vector control methods include resistance to existing insecticides and the inability to find and treat cryptic breedi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a microperforated nanocomposite balloon for intravascular anti restenotic drug delivery


    Hemodialysis is the most common treatment for kidney failure requiring the passing of blood out of the body through a filter and back into the body Almost of hemodialysis patients undergo arteriovenous graft procedures involving the insertion of prosthetic shunts i e synthetic tubes between artery and vein particularly in the forearm With the hemodialysis patient population estimated ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. SA FasL engineered human islets as a novel product for the treatment of type diabetes

    SBC: FasCure Therapeutics LLC            Topic: NIDDK

    PROJECT SUMMARY Type diabetes T D is a chronic autoimmune disorder that affects of population worldwide Exogenous insulin treatment is the standard of care for T D but often negatively affects the quality of life and is ineffective in preventing recurrent hyperglycemia episodes and chronic complications Recent studies show that human islet allografts can restore long term normoglycemia ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Delivery of Nanoencapsulated TGFbeta and ATRA for the Treatment of IBD

    SBC: THERAPYX, INC.            Topic: NIAID

    Abstract TGF NanoCap is an oral combination of nanoparticulate transforming growth factor beta TGF and all trans retinoic acid ATRA in pre clinical development for treatment of inflammatory bowel disease IBD Phase I studies provided proof of principle for efficacy in a murine model Phase II work optimized therapeutic protocol confirmed efficacy in a second model established scale up ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. AnomLoc: A perfSONAR-based Distributed Network Anomaly Detection and Localization

    SBC: INFOBEYOND TECHNOLOGY, LLC            Topic: 01a

    Data-intensive scientific applications incline to high performance computing which is getting more and more widespread in supercomputing centers, research laboratories, and universities. DoE and many organizations need an automatic and adaptive network analysis tool for effective anomaly detection and localization in the high speed network. Currently approaches, Pythia, APD, etc., are unable to pr ...

    SBIR Phase I 2017 Department of Energy

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