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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: A Chemoselective Microreactor for Breath Analysis

    SBC: Breath Diagnostics, Inc.            Topic: BM

    This SBIR phase I project seeks to address the critical need for lung cancer diagnosis at an early stage. North America has the highest age-standardized incidence of lung cancer in the world. An estimated 224,390 new cases of lung cancer will be diagnosed this year and 158,080 deaths are predicted to occur due to lung cancer in 2016. The five-year survival rate for lung cancer patients is much low ...

    SBIR Phase I 2017 National Science Foundation
  2. Harvesting specific plant metabolites from hairy root cultures using magnetized nanoparticles

    SBC: NAPROGENIX, INC            Topic: R

    Abstract Plant cell cultures are becoming a commercially valuable source of pharmaceuticals particularly those that are too complex for economical chemical synthesis For example Phyton Biotech in Germany has achieved great commercial success by generating taxoids for Paclitaxel production in sterile plant cell bioreactors However the efficiency of these systems is limited by the loss in via ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Experimental Gonococcal Vaccine

    SBC: THERAPYX, INC.            Topic: NIAID

    ABSTRACT Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and it can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent findings have revealed that ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Phase II: Feasibility assessment of a novel tool for mosquito vector control: Auto-Dissemination Augmented by Males (ADAM)

    SBC: MOSQUITOMATE, INC.            Topic: R

    Project summary abstract Mosquito control remains the primary tool for combating many mosquito vectored diseases such as Dengue Chikungunya Zika and West Nile because no approved vaccine therapeutant or prophylaxis is currently available for use Key deficiencies of existing vector control methods include resistance to existing insecticides and the inability to find and treat cryptic breedi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. SA-FasL-engineered human islets as a novel product for the treatment of type 1 diabetes

    SBC: FASCURE THERAPEUTICS, LLC            Topic: NIDDK

    PROJECT SUMMARY Type diabetes T D is a chronic autoimmune disorder that affects of population worldwide Exogenous insulin treatment is the standard of care for T D but often negatively affects the quality of life and is ineffective in preventing recurrent hyperglycemia episodes and chronic complications Recent studies show that human islet allografts can restore long term normoglycemia ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Delivery of Nanoencapsulated TGFbeta and ATRA for the Treatment of IBD

    SBC: THERAPYX, INC.            Topic: NIAID

    Abstract TGF NanoCap is an oral combination of nanoparticulate transforming growth factor beta TGF and all trans retinoic acid ATRA in pre clinical development for treatment of inflammatory bowel disease IBD Phase I studies provided proof of principle for efficacy in a murine model Phase II work optimized therapeutic protocol confirmed efficacy in a second model established scale up ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR Phase II: Biomanufacturing Red Natural Food Dye

    SBC: RedLeaf Biologics Inc.            Topic: BT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to develop natural alternatives to synthetic chemicals that are used to impart color to food, medicine, and cosmetics. Negative health impacts of some high volume synthetic colorants are driving demand for natural and safe colorants that are obtained from biological sources. This proj ...

    SBIR Phase II 2017 National Science Foundation
  8. SBIR Phase II: Low Cost Copper Contacts with Built in Barriers for Crystalline Silicon Solar Cells

    SBC: Bert Thin Films, LLC            Topic: MN

    This Small Business Innovation Research Phase II project aims to develop copper based pastes for the metallization of silicon solar cells. Photovoltaics (PV) offer an opportunity for clean and affordable energy and over the past decade the PV industry has seen annual compound growth rates of over 50%. Although revenues are high, the profit margins for many manufacturers have substantially diminish ...

    SBIR Phase II 2017 National Science Foundation
  9. AnomLoc: A perfSONAR-based Distributed Network Anomaly Detection and Localization

    SBC: InfoBeyond Technology LLC            Topic: 01a

    Data-intensive scientific applications incline to high performance computing which is getting more and more widespread in supercomputing centers, research laboratories, and universities. DoE and many organizations need an automatic and adaptive network analysis tool for effective anomaly detection and localization in the high speed network. Currently approaches, Pythia, APD, etc., are unable to pr ...

    SBIR Phase I 2017 Department of Energy
  10. Fabrication of High-quality NaA Zeolite Membranes with a Novel Plate & Frame Configuration for Molecular-scale Mixture Separations

    SBC: nGimat LLC            Topic: 15e

    Bioethanol has come into widespread use as fuel additives worldwide, especially in the U.S. and Brazil, aiming to mitigate CO2 emissions by up to 70% and sustain the carbon-neutral ecosystem. Generally, bioethanol in various fermentation broths has a maximum concentration of 6-8 wt.%. Hence, concentration of bioethanol from dilute streams poses a grand challenge from the standpoint o ...

    SBIR Phase I 2017 Department of Energy

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