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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 8034 results
  1. SBIR Phase I: Enhancing STEM Education via Virtual Reality Medical Simulation

    SBC: SimQuest International LLC            Topic: EA

    This project will explore how surgical simulation development technology may be applied to K-12 STEM education. We will develop a digital dissection based on a complete simulation of an animal specimen complete with an immersive environment, haptic feel, and accurate tissue properties. The proposed system will have the advantage of being reusable, not incurring recurring costs, being aseptic, safe ...

    SBIR Phase I 2017 National Science Foundation
  2. SBIR Phase I: Real-Time Learning Outcome Reporting

    SBC: Dig-iT Games LLC            Topic: EA

    This SBIR Phase II project represents a new approach to transparently capture and report game-based learning (GBL) outcomes that will lead to an improved understanding of the benefits of GBL as an education technology for learning science. The K-12 educational market requires a consistent reporting system for learning outcomes in GBL products while sufficiently protecting student data. Given the i ...

    SBIR Phase I 2017 National Science Foundation
  3. SBIR Phase I: Increasing Student Engagement through Adaptive Instructional Video Delivery

    SBC: PlayPosit, Inc.            Topic: EA

    This SBIR Phase II project addresses low student engagement through a dynamic video delivery environment, with a novel, real-time algorithm that adjusts the instructional pathway to each student's readiness level. Researchers consider disengaged pupils as the largest challenge facing teachers, as between 25% and 66% of students are considered to be disengaged (Taylor and Parsons 2011). As a soluti ...

    SBIR Phase I 2017 National Science Foundation
  4. Nanoengineered Hybrid Gas Sensors for Spacesuit Monitoring

    SBC: N5 Sensors, Inc.            Topic: T6.01

    Extravehicular Mobility Units (EVU) are the necessary to perform elaborate, dynamic tasks in the biologically harsh conditions of space and they have stringent requirements on physical and chemical nature of the equipment/components/processes, to ensure safety and health of the individual require proper functioning of its life-support systems. Monitoring the Portable Life Support System (PLSS) of ...

    STTR Phase II 2017 National Aeronautics and Space Administration
  5. SBIR Phase II: Kaiser Trigger: A Nano-Watt Powered Technology for Ultra-Low Power Fatigue Crack Detection

    SBC: Resensys, LLC            Topic: EW

    The broader impact/commercial potential of this project is the result of introducing a new generation of low-power wireless sensors for detecting Acoustic Emission events and detecting fatigue damage in structures. According to the Federal Highway Administration (FHWA), the US transportation infrastructure has 605,102 operational bridges, of which 66,561 are structurally deficient. In particular, ...

    SBIR Phase II 2017 National Science Foundation
  6. A Yeast based Immunotherapy against Clostridium difficile Infection

    SBC: FZATA, INC.            Topic: NIAID

    Abstract Antibacterial resistance is a global public health crisis Antibiotic resistant Clostridium difficile is responsible for more than deaths in US each year and the infection represents an urgent threat to public health worldwide Of most concern is that the incidence of C difficile infection CDI and disease severity is rapidly increasing in recent years due to the emergence of hy ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Evaluation of Natural Products and Derivatives as Antimalarial Agents

    SBC: CASCADE THERAPEUTICS, INC.            Topic: NIAID

    PROJECT SUMMARY The proposed research focuses on the development of novel therapeutic agents for the treatment of malaria caused by P falciparum Preliminary studies have discovered some novel natural products and derivative molecules with potent in vitro activity against both sensitive and multidrug resistant malaria strains including the newly emerging artemisinin resistant parasite line New ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Strategies to Improve Production of a Full-Length Native HIV-1 Env Spike

    SBC: CODEX BIOSOLUTIONS, INC.            Topic: R

    Project Summary Production of HIV envelope protein Env trimeric gp cleaved to gp gp for clinical studies is a critical objective for vaccine development Its conformational plasticity which allows it to adopt multiple conformational states important for function often makes its expression and purification very difficult Our recent work shows a route for overcoming this probl ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Serotype independent therapeutic vaccine for Streptococcus pneumoniae

    SBC: INTEGRATED BIOTHERAPEUTICS, INC.            Topic: R

    In the era of growing antibiotic resistance life threatening infections with several bacterial pathogens are cause for major concern Approved vaccines exist only for a handful of bacterial pathogens Even when a vaccine is available invasive bacterial diseases can occur due to lack of serotype coverage poor vaccine response among vaccinated populations or because many simply don t get vaccinat ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development and Validation of a Collaborative Web-Based Quantitative Imaging and Dosimetry System for Radiopharmaceutical Therapy

    SBC: RADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC            Topic: NCI

    Radiopharmaceutical therapy RPT is an emerging cancer treatment that delivers radiation directly to cancer cells The recent FDA approval of Ra Xofigotm for resistant metastatic prostate cancer and its commercial success provides an example of the therapeutic and commercial potential of this modality In addition drug companies have large libraries of targets and targeting molecules Progre ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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