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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 23070 results
  1. Intravascular Cardiac Assist System for Decompression and Recovery

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this proposal is to develop a less invasive long-term copulsation device to treat patients in late Class III and early Class IV stages of heart failure (HF). Chronic congestive heart failure is the largest unsolved problem in cardiac care today. There are over 5.5 million people in the United States with this diagnosis and the number of patient ...

    SBIR Phase II 2010 Department of Health and Human Services
  2. A Novel Polymeric Percutaneous Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this SBIR program is the modification of a polymeric trileaflet heart valve to a valve prosthesis that can be delivered percutaneously as a transcatheter aortic valve replacement. Key innovations include improved durability and hemodynamic properties, lower manufacturing costs, and simplified delivery over existing transcatheter bioprosthetic v ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Minimally Invasive Pediatric VAD for Treatment of Acute Heart Failure

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of the Pediatric Impella system, a minimally invasive ventricular assist device (VAD) for treatment of acute heart failure in pediatric patients. The device will be a less traumatic alternative to extracorporeal membrane oxygenation (ECMO), the current standard of care for these patients. T ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. PM 2.5 Emissions Reduction for Two-Stroke Engines

    SBC: Aerodyne Research, Inc.            Topic: TopicG

    Small particulate emissions, such as those that fall within the PM2.5 classification, have a substantial negative effect on air quality and human health. Significant sources of PM2.5 emissions are small two-stroke engines that are used in outdoor power equipment such as leaf blowers, chain saws, and string trimmers, as well as larger two-stroke engines used in recreational vehicles such as all-ter ...

    SBIR Phase I 2010 Environmental Protection Agency
  5. CMR Oxides Based Microbolometer Focal Plane Array with Reduced 1/f Noise

    SBC: AGILTRON, INC.            Topic: ARMY09T014

    We propose to realize a new class of microbolometer FPA technology with significantly reduced 1/f noise by replacing the sensing material (e.g. VOx) with colossal magnetoresistive (CMR) oxides. The program uniquely combines Agiltron's experience in novel IR imager development and leading academic research on CMR at Los Alamos National Lab (LANL). The LANL Team has developed breakthrough process ...

    STTR Phase II 2010 Department of DefenseArmy
  6. Compact Chemical Sensor for Measurement of Internal Dose of Environmental Agents

    SBC: AGILTRON, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Detection of exposure to environmental agents by measurement of internal dose of such agents or their metabolites, chemical or biological, requires rapid assessment and identification of exposure to both known and unknown threats. Fast detection and identification of exposure to such threats can provide prompt warning of the extent and severity of the exposure ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. High Performance Detectors for SPECT

    SBC: Radiation Monitoring Devices, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): High Performance Detectors for SPECT P.I.: Dr. Michael R. Squillante Abstract Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional distribution of a radionuclide throughout the body of a human patient or a research animal. Typically, the collected data are d ...

    SBIR Phase II 2010 Department of Health and Human Services
  8. High Speed and High Sensitivity Quadrant Photo Detector

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    To further advance the characterization and utility of microcantilevers, next generation optical detectors with higher frequency response, improved displacement resolution and lower noise for weak signal detection are needed. Consequently, Radiation Monitoring Devices, Inc. (RMD) will develop a turnkey optical detector module for use in characterizing the displacement and resonant frequencies of m ...

    SBIR Phase I 2010 Department of CommerceNational Institute of Standards and Technology
  9. Photonic Bandgap Structures for Improved Timing and Spatial Resolution in PET Det

    SBC: Radiation Monitoring Devices, Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Scintillation crystals coupled to photomultiplier tubes or silicon diodes are the most common detectors for X-ray/3-ray detection. Imaging modalities such as positron emission tomography (PET), single photon emission computed tomography (SPECT), digital radiography (including digital mammography) and X-ray CT are critically important for cancer diagnosis, stagi ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. New Design of a Sensor for Ultrahigh Performance SPECT Imaging

    SBC: Radiation Monitoring Devices, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Among the various functional imaging techniques, SPECT maintains an important and growing role in the study of disease models in small animals as well as in patient care. Many SPECT-labeled imaging probes that have highly specific distributions with very little background are being used to measure a wide range of biological parameters of importance in small ani ...

    SBIR Phase I 2010 Department of Health and Human Services

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