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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. An Artificial Myocardium for Pediatric Support

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposed program is the commercialization of a neonate ventricular assist device (VAD). Although VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in small infan ...

    SBIR Phase II 2006 Department of Health and Human Services
  2. ECM Bioscaffold for ASD Repair

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I proposal seeks support to evaluate the feasibility of developing an extracellular matrix (ECM) biologic scaffold as a repair device for atrial septal defects (ASD). ASDs are one of the most common forms of congenital heart disease and account for approximately 30-40% of all congenital heart defects seen in adults. Closure of an ASD can be performed ...

    SBIR Phase I 2006 Department of Health and Human Services
  3. Directed Differentiation of Embryonic Stem Cells using Phage Displayed Ligands

    SBC: OCATA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to culture human embryonic stem cells generated a great deal of excitement about their vast potential for treating a variety of human diseases such as diabetes, heart disease, neurological, retinal and skin disorders to name a few. Unlike adult stem cells, embryonic stem cells have indefinite growth potential and the potential to develop into any t ...

    STTR Phase I 2006 Department of Health and Human Services
  4. Clinical study of GMCI in Pancreatic Cancer

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Pancreatic adenocarcinoma is the fourth leading cause of cancer deaths in the US; with less than one-year median survival, it accounts for approximately 30,000 diagnoses and deaths per year. Multimodality therapy, including surgery, radiation and chemotherapy, have not made a significant impact on the outcome and serve mostly as palliation. Thus, new treatment ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Pneumoreductive Surfactant Therapy for Emphysema

    SBC: AERIS THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Aeris therapeutics is developing a novel medical treatment for patients with advanced emphysema known as Pneumoreductive Surfactant (PRS). PRSs are inhaled drugs that increase lung recoil by safely altering the surface tension properties of native lung surfactant. Unlike existing medical therapies for chronic obstructive pulmonary disease, PRS is the only medi ...

    SBIR Phase II 2006 Department of Health and Human Services
  6. Solid State Beta Imaging Sensor for Radioguided Surgery

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Advances in radiopharmaceutical have dramatically escalated the use of intraoperative gamma probes in surgery. Such probes provide benefits of increased tissue specificity obtained for biopsy, minimally accessed incisions, and the reduction of inpatient hospital utilization with an improved patient recovery. At present most of the probes on the market are non-i ...

    SBIR Phase II 2006 Department of Health and Human Services
  7. NearIR Photon-counting Camera for Diffuse Optical Tomography

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Early detection and routine clinical screening represent the first line of defense for managing cancer, a disease that claimed over 570,280 lives in the U.S. during the year 2005. Significant advances have been made in the medical imaging of tumors; however, many of these techniques are too expensive to be implemented for routine screening. Diffuse optical tomo ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. Species Level Identification of Pathogenic Viruses on a Microfluidic Platform

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Radiation Monitoring Devices, Inc. (RMD) proposes to develop a field-portable instrument for the detection and identification of pathogenic viruses that are collected by an aerosol concentrator. It will incorporate modular, microfluidic platforms designed to capture and concentrate the sample for a rapid, two-stage analysis. The first employs pathogen capture o ...

    SBIR Phase II 2006 Department of Health and Human Services
  9. PET Detector for Cardiac Imaging of Small Animals

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron emission tomography (PET) of small animals is emerging as a very powerful tool for advancing our understanding of human diseases such as heart disease and cancer. Due to the small (sub-millimeter) feature sizes, dedicated, high resolution PET systems are required to obtain sufficiently detailed images of organs of interest. In particular, sub-millimete ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. High Sensitivity Pesticide and Nerve Agent Detector

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): RMD Inc. proposes to develop direct reading, highly sensitive, reusable point sensors for detecting organophosphate and carbomate pesticide and nerve agent contamination in liquid and air. The sensors can be made for visual detection and handheld instrument readout using absorbance and fluorescence transduction modes, and will be suitable for unattended continu ...

    SBIR Phase I 2006 Department of Health and Human Services

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