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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 6570 results
  1. Assistive Technology Enabling Communication

    SBC: Pison Technology, Inc.            Topic: na

    This project furthers development of an effective early-stage assistive communication device for patients with Amyotrophic Lateral Sclerosis (ALS). The wearable assistive communication device uses electromyography (EMG) signals to empower users with ALS and other neuromuscular disabilities to control household devices (e.g. computers) and communicate within their environment. Increasing the capabi ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. SoundFit Ultrasonic Performance Diagnostic for Lower-Body Prostheses

    SBC: FTL Labs Corporation            Topic: na

    This project develops an ultrasonic fitment tool to improve prosthetics performance for persons with lower-extremity amputations. The goal of this project is to develop a new clinical instrument used in the socket fitting process to optimize the performance of a lower-body prosthetic system and thereby improve mobility, activity, exercise, and quality of life for over 2 million American amputees. ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Thermostable Savin IPV

    SBC: Luna Innovations Incorporated            Topic: ODCDC

    PoliomyelitisPoliois a highly infectious disease that primarily affects young childrenCurrentlythe live attenuated oral poliomyelitis vaccineOPVis the vaccine used to prevent polio outbreaks and stop transmission of wild poliovirusesHoweversometimes OPV has the ability to revert to a form that can cause paralysis or poliomyelitiswhich will inevitably lead to new polio outbreaksIn most developed co ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Development of Rapid Antigen Detection Assays For Taeniasis

    SBC: Kephera Diagnostics, LLC            Topic: ODCDC

    This proposal addresses the significant public health threat posed by the spread of Taenia soliumthe pork tapewormin at risk human populationsInfection with Tsoliumor Taeniasiscan lead to Cysticercosiscaused by the migration and encystment of larval Tsolium in the central nervous systemCysticercosis is a severe to fatal disease which affects overmillion people worldwideprincipally in less develope ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Synergistic Antifungal Cocktails for Corneal Storage

    SBC: Giner, Inc.            Topic: ODCDC

    Fungal endophthalmitis is an infection inside the eye after corneal transplant surgery caused by contamination of the transplanted tissueAccording to the Eye Bank of Americathe incidence of postsurgery endophthalmitis more than doubled fromtoand thatof the culture positive cases were due to Candida yeastEnvironmental contamination as well as current corneal preservation conditions contribute to th ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Self Stable Corneal Tissue Storage Solutions with Antifungal Additives

    SBC: Luna Innovations Incorporated            Topic: ODCDC

    There has been a recent rise in the rate of fungal infections following corneal transplant surgeries over the last six yearsand most cases have been tied to donor to recipient transmissionWhile preliminary studies have demonstrated the efficacy and safety of adding antifungal agents to the corneal storage media to minimize the risk of infectionthe shelf life of these antifungal agents is significa ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Topic 378: Symptomatic Toxicity Mobile Monitor (SympTMM)

    SBC: Vivonics, Inc.            Topic: NCI

    The goal of this NIH Phase I SBIR proposal is to develop and validate a new method to monitor the symptomatic toxicities and health-related quality of life of cancer patients who are undergoing and have undergone radiation therapy during the course of their treatment. The proposal is built around expertise in mobile application development (Vivonics Inc.) and radiation oncology (Dr. TJ Fitzgerald ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Topic 378: PRORAD- A Mobile Application for Patient Related Outcomes of Radiotherapy

    SBC: Charles River Analytics, Inc.            Topic: NCI

    Cancer patients receiving radiation therapy experience toxic side effects of the radiation, and sensitivity to radiation is variable across both patients and tumors, and is poorly understood. This Phase I SBIR project aims to design and demonstrate the feasibility of a Patient Reported Outcome mobile application for surveillance of RADiotherapy toxicity (PRORAD) that integrates NIH's Patient Repor ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 374: Sustained Delivery of PARP Inhibitors for Cancer Chemoprevention

    SBC: TheraNano LLC            Topic: NCI

    Here we propose to study two injectable formulations that provide different delivery routes for Talazoparib, potent PAPR inhibitor: An implant, InCeT-Talazoparib, which can be injected directly in the tumor where it will act as a sustained release depot of Talazoparib over a prolonged period of approximately 30 days. It delivers 100% of the drug to the tumor site with almost no systemic toxicity. ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)

    SBC: Imago Systems, Inc.            Topic: NCI

    Immunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy. In this Contract, Imago Systems, Inc., a company with substantial experience i ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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