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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. ULTRAMINIATURE IMPLANTABLE ELECTRICAL CONNECTOR

    SBC: ABIOMED, INC.            Topic: N/A

    THE OBJECTIVE OF THIS PROPOSAL IS THE DEVELOPMENT OF A MINIATURE ELECTRICAL CONNECTOR SUITABLE FOR PERMANENT IMPLANTATION IN THE BODY. SUCH A DEVICE IS INTENDED TO SERVE AS A CONNECT/DISCONNECT POINT FOR NEURAL PROSTHESES, ENABLING REPLACEMENT OF FAULTY COMPONENTS WITHOUT NECESSITATING REMOVAL OF AN ENTIRE IMPLANTED SYSTEM. SEVERAL DIFFERENT ELECTRICAL CONNECTORS HAVE BEEN DEVELOPED IN CONJUNCTION ...

    SBIR Phase II 1989 Department of Health and Human Services
  2. SURFACE MODIFICATION OF ABSORBABLE SUTURE MATERIALS

    SBC: AST PRODUCTS, INC.            Topic: N/A

    THE BASIC FUNCTION OF A SURGICAL SUTURE IS TO MAINTAIN TISSUE APPROXIMATION UNTIL THE WOUND HEALS. IDEALLY, UPON HEALING, THE SUTURE SHOULD DISAPPEAR, LEAVING NO TRACE OF ITS PRIOR EXISTENCE AND THUS MINIMIZING UNDESIRABLE FOREIGN BODY REACTIONS. RECENTLY, SEVERAL SYNTHETIC ABSORBABLE POLYMERIC SUTURE MATERIALS WERE DEVELOPED THAT DEMONSTRATED SATISFACTION FOR MOST OF THE WOUND CLOSURE REQUIREMENT ...

    SBIR Phase I 1989 Department of Health and Human Services
  3. NOVEL BIOELECTRODE FOR NEUROSCIENCE APPLICATIONS

    SBC: AST PRODUCTS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services
  4. EFFICIENT SYNTHESIS OF INDOLACTAM-TYPE PKC ACTIVATORS

    SBC: Alder Research Center            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services
  5. REAL TIME IMAGING SYSTEM FOR SCREENING DNA LIBRARIES

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ONE OF THE MOST ACTIVE AND CHALLENGING FIELDS IN MOLECULAR BIOLOGY TODAY IS THE GENETIC STUDY OF EUKARYOTIC SYSTEMS. AN ESSENTIAL, BUT OFTEN RATE LIMITING STEP IN THIS AREA IS THE SCREENING OF DNA LIBRARIES FOR GENE MAPPING. THIS PROCEDURE USES RADIOLABEL HYBRIDIZATION TECHNIQUES AND AUTORADIOGRAPHY TO ACHIEVE THE REQUIRED SENSITIVITY AND SPECIFICITY. THE PARTICULAR PART OF THE PROCESS THAT THIS P ...

    SBIR Phase II 1989 Department of Health and Human Services
  6. RENAL BLOOD FLOW MONITOR FOR ICU PATIENTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ACUTE RENAL FAILURE IS A MAJOR CONTRIBUTING CAUSE OF DEATH IN PATIENTS IN THE INTENSIVE CARE UNIT PARTLY DUE TO THE LACK OF A SIMPLE, RAPID METHOD OF ASSESSING KIDNEY FUNCTION. IT WOULD THEREFORE BE EXTREMELY USEFUL IF A DIRECT MEASUREMENT OF RENAL FUNCTION COULD BE PERFORMED AT REGULAR INTERVALS SO THAT THE NEED FOR ANY MEDICAL OR SURGICAL INTERVENTION COULD BE IDENTIFIED BEFORE ANY SIGNIFICANT D ...

    SBIR Phase II 1989 Department of Health and Human Services
  7. POSITRON PROBE FOR CORNEAL TUMOR BIOASSAY

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    RECENTLY, PRELIMINARY RESEARCH USING CYCLOTRON-PRODUCED, POSITRON-EMITTING RADIOLABELS HAS BEEN CONDUCTED AT THE MEMORIAL SLOAN-KETTERING CANCER CENTER TO DEVELOP A RABBIT/RAT CORNEAL IMPLANT METHOD TO STUDY HUMAN TUMOR ANGIOGENESIS AND METABOLISM. THIS TECHNIQUE IS DESIGNED TO DETERMINE THE DIRECT IMPACT OF CHEMOTHERAPEUTIC STRATEGIES ON HUMAN BRAIN TUMORS. IT IS HOPED THAT DRUG SCREENING FOR PAT ...

    SBIR Phase I 1989 Department of Health and Human Services
  8. COMPENDIUM OF RADIATION TREATMENT ACCESSORIES

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    RADIATION THERAPY HAS BECOME ONE OF THE MOST IMPORTANT TOOLS FOR THE CONTROL OF CANCER, AND AN IMPRESSIVE ARRAY OF SUPPORTING TECHNOLOGIES HAS BEEN DEVELOPED. WHILE MANY OF THESE ACCESSORIES ARE READILY AVAILABLE FROM COMMERCIAL SOURCES, A VERY SIGNIFICANT NUMBER OF THERAPY AIDS HAVE BEENDEVELOPED AT INDIVIDUAL TREATMENT CENTERS AND ARE NOT AVAILABLE COMMERCIALLY, NOR WIDELY KNOWN. THIS SITUATION ...

    SBIR Phase I 1989 Department of Health and Human Services
  9. SOLID-STATE DETECTOR FOR CAPILLARY ELECTROPHORESIS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    GEL ELECTROPHORESIS IS ONE OF THE MOST IMPORTANT AND WIDELY USED ANALYTICAL TECHNIQUES FOR THE DETERMINATION OF THE SEQUENCE OF DNA. RECENTLY, THERE HAS BEEN A SIGNIFICANT ADVANCE IN ELECTROPHORESIS TECHNOLOGY THROUGH THE USE OF GEL GEOMETRIES INVOLVING THIN CAPILLARY TUBES. THIS TECHNOLOGY HAS BEEN DEVELOPED INTO A NEW SEPARATION TECHNIQUE, CAPILLARY ZONE ELECTROPHORESIS (CZE), WHICH PROVIDES MUC ...

    SBIR Phase I 1989 Department of Health and Human Services
  10. NEW HIGH-Z SEMICONDUCTOR SENSOR FOR POSITRON TOMOGRAPHY

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1989 Department of Health and Human Services

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