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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Polymeric Trileaflet Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to produce a fully characterized polyurethane heart valve prosthesis that will be ready for clinical evaluation. Existing replacement valves suffer from several shortcomings. Specifically, biological tissue fixation and methods used to mount the tissue to the supporting stent of bioprostheses cause time dependent structural changes ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. BIOACTIVE POLYMER FOR VENTRICULAR ASSIST DEVICES- SBIR TOPIC #37

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Improved system for producing adenoviral vectors

    SBC: ADVANTAGENE, INC            Topic: N/A

    First generation non-replicative adenoviral vectors show promise as anti-cancer agents and as prophylactic vaccines. Current methods for manufacturing these vectors use either the 293 cell line or the PER.C6 cell line. These producer cells provide complementary E1a and E1b viral function in the cell for disabled adenoviral vectors. The 293 cell line has been very useful and widely used for mak ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Clinical and Immunologic Evaluation of ProstAtak for Prostate Cancer

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to develop a new therapeutic to improve the outcome for patients with intermediate-risk prostate cancer. The indication is a first-line adjuvant to be combined with radiation therap y for prostate cancer. The desired outcomes are improved local control rate, decreased recurrence and improved disease-free survival. This gran ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Clinical study of AdV-tk radiogenetherapy for malignant*

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Malignant gliomas have a very poor prognosis with median survival measured in months rather than years. It is a disease with great need of novel therapeutic approaches. Within cancer gene therapy the use of adenoviral vectors to deliver HSV-tk (AdV-tk) has been one of the most widely studied and promising approaches. A few dose escalation Phase I studies ha ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Unresolved Resident Space Object (RSO) Characterization Using Time-Frequency Analysis

    SBC: ATMOSPHERIC & ENVIRONMENTAL RESEARCH, INC.            Topic: AF071283

    Defense of U.S. space assets depends on the successful detection and monitoring of potential threats, including the ability to recognize abnormal spacecraft activities. Although work has been done in this area using resolved images from ground- and space-based sensors, methodologies to characterize unresolved resident space objects (RSO) have received little attention. We propose to develop tech ...

    SBIR Phase I 2007 Department of DefenseAir Force
  7. Real-Time Specification of Battlespace Environment

    SBC: ATMOSPHERIC & ENVIRONMENTAL RESEARCH, INC.            Topic: AF06248

    A system is proposed for real-time specification of the Battlespace Environment and integrated sensor management designed to optimize the joint operational capabilities of radio-frequency (RF), electro-optical (EO) and infrared (IR) sensors in the detection, tracking, surveillance, and characterization of space objects. To meet this objective, we present a framework for integrating phenomenologica ...

    SBIR Phase II 2007 Department of DefenseAir Force
  8. Chemical Quick-Quench Probe for Aircraft Engine Emissions Measurements

    SBC: AERODYNE RESEARCH INC            Topic: AF05301

    The chemical composition of the exhaust streams of aircraft engines (augmented and non-augmented) and combustors are required for the determination of combustion efficiency and for understanding pollutant formation. Typically, extractive sampling is used to measure aircraft emissions; however, these measurements are biased by chemistry that can occur as the gas sample travels through the probe and ...

    SBIR Phase II 2007 Department of DefenseAir Force
  9. Breath Analysis using Quantum Cascade Lasers

    SBC: AERODYNE RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of components in human breath is a powerful non-invasive technique for the diagnosis and monitoring of asthma, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The presence of elevated levels of nitric oxide (NO), carbon monoxide (CO), carbonyl sulfide (OCS), and ethane (C2H6) in the breath have been identified as biomarkers o ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Precision and Stable Fiber Optical Gyroscope Made of Air-Core Fiber

    SBC: AGILTRON, INC.            Topic: AF071216

    Agiltron proposes to systematic study the un-stable mechanisms, leading to the establishment of space qualification procedure for fiber optic gyros (FOGs). The approach leverages our industry experiences in satellite FOG component and sensor system fabrication. This program will lead to development of a certification service for the air-core photonic band-gap fiber components and navigation-grade ...

    SBIR Phase I 2007 Department of DefenseAir Force
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