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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Bioactive Polymer Designed for Cardiac Assist Devices

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. An Artificial Myocardium for Pediatric Support

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. Brain Trauma Assessment System

    SBC: Active Signal Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): With over 1.5 million persons suffering head injury annually in the U.S., and approximately 50,000 dying from these injuries, a need exists for early direct assessment of brain injury. Currently, injuries must be inferred from Glascow Coma Scores (GCS), low blood pressure, and/or low pulse oximetry, but there is no direct method of measuring brain condition at ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Safety-Sensing Independence-Enhancing Wheelchair

    SBC: MOBILEROBOTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Serious wheelchair accidents have risen to almost 37,000 per year. Users of power chairs are three times as likely to have accidents as users of manual chairs! Many people can neither walk nor successfully navigate a wheelchair, e.g., many with MS, quadraplegia, spinal stenosis, visual and other impairments. The Safety Sensing Independence-Enhancing Wheelch ...

    SBIR Phase II 2003 Department of Health and Human Services
  5. New Agents That Inhibit Fatty Acid Accumulation

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Activators of Adipocyte Fatty Acid Oxidation

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Development of Ultrasonic Appratus for Dental Diagnosis

    SBC: AAC International            Topic: N/A

    DESCRIPTION: An ultrasonic diagnostic apparatus has been proposed for Dental applications in determining tooth pathologies such as demineralization/caries, hidden fractures, and formation of abscesses. The equipment adopts a piezoelectric and laser optic hybrid transduction system for interrogation of teeth. Ultrasonic responses of the tooth structure will be analyzed by a pattern recognition expe ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. Development of Ultrasonic Appratus for Dental Diagnosis

    SBC: AAC International            Topic: N/A

    DESCRIPTION: An ultrasonic diagnostic apparatus has been proposed for Dental applications in determining tooth pathologies such as demineralization/caries, hidden fractures, and formation of abscesses. The equipment adopts a piezoelectric and laser optic hybrid transduction system for interrogation of teeth. Ultrasonic responses of the tooth structure will be analyzed by a pattern recognition expe ...

    SBIR Phase II 2003 Department of Health and Human Services
  9. Combination of GM-CSF with TKR gene therapy

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Combined gene therapy (Herpes Simplex Virus Thymidine Kinase + Anti-herpetic Prodrug) and radiation therapy (TKR therapy) is a novel approach in the armamentarium against cancer. This radio-gene therapy combination creates a new spatial co-operation whereby two local treatment modalities have demonstrated enhanced local and metastatic tumor control and prolong ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Biothreat Detection with Improved Background Rejection

    SBC: Aerodyne Research, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The Quartz Crystal Microbalance (QCM) is a well-established technology for quantifying small changes in mass. The long-term objective of this program is to improve the QCM so that it is suitable for use as a field test for the common, foodborne bacteria. To do this, we will modify the standard quartz crystal (QC) used in the QCM so as to increase its background ...

    SBIR Phase I 2003 Department of Health and Human Services

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