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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A universal TET system for implanted life support systems

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposed program is the commercialization of a universal transcutaneous energy transfer (TET) system with a high performance implantable battery. This integrated power system will be adapt able to a host of next generation fully implantable mechanical circulatory support (MCS) systems. To date, fully implantable systems (i.e. the ...

    SBIR Phase II 2008 Department of Health and Human Services
  2. Novel Catheter for Treatment of Ventricular Tachycardia

    SBC: Thermedical Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Ischemic ventricular tachycardia (VT) is a contributing cause to more than half of the 300,000 sudden cardiac deaths that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the stand ard therapy but they are expensive the total cost of an ICD implant approaches 50,000 and the United States spends more than 2.2B on these im ...

    SBIR Phase II 2008 Department of Health and Human Services
  3. Defining Therapeutic Potential of Clonal Stem Cell Populations using Targeted Nan

    SBC: OCATA THERAPEUTICS, INC.            Topic: N/A

    Project Summary Embryonic stem cells offer considerable potential for cell replacement therapy where cells have been lost to injury or disease because of their capacity for continual self renewal and ability to differentiate into virtually any cell type or tissue. Currently, however the process by which human embryonic stem cells (hESCs) differentiate into various mature functional cell types is ...

    SBIR Phase I 2008 Department of Health and Human Services
  4. iGenomeTM Software Platform Prototype for Individual Genetic Health Assessment

    SBC: 3RD MILLENNIUM, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Sufficient general clinical knowledge, DNA sequence technology and understanding of genetic mutations for over 2,600 human genes can support beginning the integration of individual genome sequence into clinical practic e for a number of medical specialties. With the 2007 deployment of novel DNA sequence technologies that permit cost-effective interrogation of ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Real-Time Image and Dose Guided Radiation Therapy System

    SBC: ADVANCED RADIATION THERAPY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Real-Time Image and Dose Guided Radiation Therapy System Development and integration of a real-time image- and dose-guided radiation therapy system is long overdue. Advanced Radiation Therapy has identified an opportuni ty and designed a single system that uses a common platform for imaging the target tissue in real-time, immobilizing the tissue, delivering rad ...

    SBIR Phase I 2008 Department of Health and Human Services
  6. Inhaled nisin as an emergency intervention against antibiotic sensitive or resist

    SBC: AFG BIOSOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The deliberate release of Bacillus anthracis spores remains an imminent threat both in terms of bioterrorism and biowarfare. Individuals who inhale these spores are at extreme risk of infection and death from anthrax. C urrent prophylaxis and therapy in the event of B. anthracis spore inhalation fall into two categories. Vaccination to protect against future ex ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. Add-on module for ONCAD for diagnosing infiltrating lobular carcinoma

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this study is to develop an add-on module for the ONCAD breast MRI CAD system that will provide radiologists with additional assistance when they have suspicion of the presence of infiltrating lobula r carcinoma (ILC). The proposed research will investigate the possibility of developing, training and evaluating an ILC- specific algorithm tha ...

    SBIR Phase I 2008 Department of Health and Human Services
  8. High Resolution Mammography Sensor

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Radiation Monitoring Devices ( RMD') is developing a digital radiographic imaging technology that is based upon a semiconductor x-ray receptor. The more specific, targeted application is mammographic imaging (including breast tomosynthesis) for which the benefits of this technology will later be described. At the core of this research, RMD is developing the pr ...

    SBIR Phase II 2008 Department of Health and Human Services
  9. Position Sensitive Microfluidic Detector

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Microfluidic chips, fabricated from low cost polymers, are a promising, emerging technology for synthesis and study of new molecular imaging probes. These chips can contain a variety of microcircuitry and microwells and are capable of manipulating nanoliter samples of reagents and solvents. The microfluidic chips have been designed for a multitude of applicati ...

    SBIR Phase I 2008 Department of Health and Human Services
  10. A New High Performance Detector for Small Animal SPECT

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Among the various functional imaging techniques, SPECT maintains an important role in the study of disease models in small animals as well as in patient care. Many SPECT-labeled imaging probes that have highly specific distributions with very little background are being used to measure a wide range of biological parameters of importance in small animals inclu ...

    SBIR Phase II 2008 Department of Health and Human Services

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