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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Anastomotic Device for Large Vascular Grafts

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposed program is to develop a general purpose anastomotic device for large vessels and vascular grafts, based on a novel stapler design. The use of the device can provide an alternative procedure to the current manual suturing methods, with the potential of yielding anastomoses having better and more reproducible performance, and with r ...

    SBIR Phase I 2009 Department of Health and Human Services
  2. Intraventricular Cardiac Assist System for Decompression and Recovery

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of an advanced intraventricular cardiac assist system for cardiac unloading and recovery. This type of ventricular assist device (VAD) will provide the optimal support for recovery for acute heart failure patients, and may be useful for a select group of chronic heart failure patients suppo ...

    SBIR Phase I 2009 Department of Health and Human Services
  3. Novel Small Molecule Inhibitor of Rheumatoid Arthritis

    SBC: A&G PHARMACEUTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Lck is a Src family non-receptor tyrosine kinase expressed by T lineage lymphocytes. In T cells, Lck plays an essential role in the generation of antigen-mediated activation signals. Since T cell activation is central to mounting immune response, inhibition of Lck blocks T cell activation and suppresses the immune response. Accordingly, Lck serves as an ideal ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. Label-free Multiplexed Immunoassay Platform for Diagnosing Liver Disease

    SBC: ZOIRAY TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the present work is to demonstrate a label-free multiplexed immunoassay platform liver disease diagnosis. The method is to integrate multiple tests for serum antigens and antibodies onto a single disposable chip that could be used with the instrument for about the cost of one or a few current immunoassays that identify the presence of just one marke ...

    SBIR Phase I 2009 Department of Health and Human Services
  5. Label-Free Protein Array for Alzheimer's Disease Detection and Monitoring

    SBC: ZOIRAY TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose the development of a single-chip, multiplexed, label-free platform for Alzheimer's disease diagnosis and monitoring of protein markers in the cerebral spinal fluid (CSF). The Spectral Reflectance Imaging Biosensor is a label-free protein array technology that can monitor real-time binding label-free at more than 1000 locations simultaneously. A uniq ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Clinical and Immunologic Evaluation of ProstAtak for Prostate Cancer

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to develop a new therapeutic to improve the outcome for patients with intermediate-risk prostate cancer. The indication is a first-line adjuvant to be combined with radiation therapy for prostate cancer. The desired outcomes are improved local control rate, decreased recurrence and improved disease-free survival. This grant ...

    SBIR Phase II 2009 Department of Health and Human Services
  7. Nitrogen Dioxide and Light-Absorbing Carbon Sensors for Personal Exposure Assessm

    SBC: Aerodyne Research, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This project addresses the need for the development of field deployable, sensors which provide real- time quantitative measurements at point-of-contact of airborne species that are injurious to human health - in this particular case, nitrogen dioxide and light-absorbing carbon. Nitrogen dioxide (NO2) is a highly toxic gas which when inhaled, causes the formati ...

    SBIR Phase I 2009 Department of Health and Human Services
  8. Miniature, rapid, and 3-dimensional OCT scanner for dental imaging

    SBC: AGILTRON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Agiltron proposes an innovative dental OCT (optical coherence tomography) miniature probe with a unique and high speed 2D MEMS scanner. This will enable the miniaturization of the two dimensional probe, so that dentist need only hold a probe in a fixed position against a tooth and obtain a complete three dimensional scan of the structure in less than one second ...

    SBIR Phase I 2009 Department of Health and Human Services
  9. Portable High Resolution Detector for Rapid Field Arsenic Test in Drinking Water

    SBC: AGILTRON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Agiltron propose to develop a Portable High Resolution Detector for Rapid Field Arsenic Test in Drinking Water, based on Surface-Enhanced Raman Spectroscopy (SERS) and Nanostructured SERS substrates. In Phase I of the p rogram, we will demonstrate feasibility by fabricating SERS substrates based on Langmuir-Blodgett monolayer assembly of highly crystalline silv ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Information Technology Enabled Treatment of Adolescent Depression

    SBC: VERITAS HEALTH SOLUTIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR application proposes development of an Information Technology Enabled Disease Management System for Treatment of Adolescent Depression (ITEMS-TAD). The need for this system innovation arises from the substantial costs that inadequately treated adolescent Major Depressive Disorder (MDD) has on the course of adolescent development and society as a whole ...

    SBIR Phase I 2009 Department of Health and Human Services

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