List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Novel Polymeric Trileaflet Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to produce a fully characterized polyurethane heart valve prosthesis that will be ready for clinical evaluation. Existing replacement valves suffer from several shortcomings. Specifically, biological tissue fixation and methods used to mount the tissue to the supporting stent of bioprostheses cause time dependent structural changes ...

    SBIR Phase II 2007 Department of Health and Human Services
  2. Sleep Apnea Identification & Treatment in Dentistry

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA), a highly prevalent, under-diagnosed disorder affecting over 18 million Americans, is responsible for more mortality and morbidity than any other sleep disorder. Dentists are increasingly involved with the treatment of OSA with oral appliances, an accepted treatment of OSA for patients with mild to moderate disease severity and for ...

    SBIR Phase II 2007 Department of Health and Human Services
  3. Clinical study of AdV-tk radiogenetherapy for malignant*

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Malignant gliomas have a very poor prognosis with median survival measured in months rather than years. It is a disease with great need of novel therapeutic approaches. Within cancer gene therapy the use of adenoviral vectors to deliver HSV-tk (AdV-tk) has been one of the most widely studied and promising approaches. A few dose escalation Phase I studies ha ...

    SBIR Phase II 2007 Department of Health and Human Services
  4. Breath Analysis using Quantum Cascade Lasers

    SBC: Aerodyne Research, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of components in human breath is a powerful non-invasive technique for the diagnosis and monitoring of asthma, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The presence of elevated levels of nitric oxide (NO), carbon monoxide (CO), carbonyl sulfide (OCS), and ethane (C2H6) in the breath have been identified as biomarkers o ...

    SBIR Phase II 2007 Department of Health and Human Services
  5. Study of CdZnTe Electrode Interface and Fabrication Technology Development

    SBC: Aguila Technologies, Inc.            Topic: N/A

    Not avaiable.

    STTR Phase II 2007 Department of Health and Human Services
  6. OpenClinica: Open Source Platform for Clinical Research

    SBC: AKAZA RESEARCH            Topic: N/A

    DESCRIPTION (provided by applicant): We believe a key barrier to transforming clinical research is the lack of open, integrated, transparent technology solutions that address bottlenecks in information integration and business process management. Our viewpoint is supported by a recent Forrester Research study that identifies proprietary software as "one of the biggest barriers" to interoperability ...

    SBIR Phase II 2007 Department of Health and Human Services
  7. High-Speed Micro CT Detector for Physiologic Studies

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Dedicated high-resolution small animal imaging systems have recently emerged as important new tools for cancer research. Of these systems, x-ray microcomputed tomography (microCT) shows promise as a cost-effective means for detecting and characterizing soft tissue structures, skeletal abnormalities, and tumors in live animals. Existing CT systems provide high-r ...

    SBIR Phase II 2007 Department of Health and Human Services
  8. HIGH RESOLUTION NUCLEAR CARDIAC IMAGING

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Nuclear medicine imaging modalities such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) are powerful, non-invasive medical imaging techniques that provide an image of the three dimensional distribution of a radionuclide in any slice through an organ under study in the body. These images allow investigation of metab ...

    SBIR Phase II 2007 Department of Health and Human Services
  9. High Resolution PET Detectors for Combined PET-MR Small Animal Imaging

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The ideal biological imaging system would provide non-invasive, high-resolution, high-sensitivity, three-dimensional (3D) functional and anatomic images of living systems. Positron Emission Tomography (PET) offers high sensitivity to a range of biological processes through the use of targeted radiolabeled probes. Unfortunately, precise signal localization can b ...

    SBIR Phase II 2007 Department of Health and Human Services
  10. Digital 2-D Neutron Detector for Protein Function Studies

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Information on the structure and function of proteins is important for unveiling biological processes taking place on a molecular level. X-ray crystallography has been successful in determining protein structure, however, it is not well suited for analyzing hydrogen atoms and water molecules. It has been shown that the thermal neutrons are a far better tool for ...

    SBIR Phase II 2007 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government