Award Data

DESCRIPTION (provided by applicant): The goal of this proposal is to produce a fully characterized polyurethane heart valve prosthesis that will be ready for clinical evaluation. Existing replacement valves suffer from several shortcomings. Specifically, biological tissue fixation and methods used to mount the tissue to the supporting stent of bioprostheses cause time dependent structural changes ...

N/A

DESCRIPTION (provided by applicant): The generation, manipulation, storage and retrieval of chemical structures and subsequent calculation of various properties, often related to their biological activity, have become extremely important for drug discovery. The resulting field of Cheminformatics has blossomed in recent years and has been a hotbed for the application of data mining and database pri ...

DESCRIPTION (provided by applicant): This STTR proposal to the National Institute on Aging (NIA) requests funding to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen LLC with earlier support from NIA. The purpose of MedRIC is to facilitate the acquisition and linking of administrative data from the Centers for Medicare and Medicaid Service ...

DESCRIPTION (provided by applicant): This STTR proposal to the National Institute on Aging (NIA) requests funding to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen LLC with earlier support from NIA. The purpose of MedRIC is to facilitate the acquisition and linking of administrative data from the Centers for Medicare and Medicaid Service ...

DESCRIPTION (provided by applicant): Alterations in neurocognitive function play a major role in numerous sleeps, neurological and psychiatric disorders and can have a significant impact on quality of life, treatment efficacy, rehabilitation and ability to function at work and in normal daily activities. The methods currently available for neurocognitive investigations including traditional neur ...

DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA), a highly prevalent, under-diagnosed disorder affecting over 18 million Americans, is responsible for more mortality and morbidity than any other sleep disorder. Dentists are increasingly involved with the treatment of OSA with oral appliances, an accepted treatment of OSA for patients with mild to moderate disease severity and for ...

DESCRIPTION (provided by applicant): Intradialytic hypotension (IDH) is associated with increased morbidity and mortality and causes delays in patient care during and immediately after dialysis. It remains one of the most vexing problems associated with dialysis therapy, occurring in approximately 25% of all dialysis treatments, affecting 75,000 patients and twelve million hemodialysis sessions pe ...

DESCRIPTION (provided by applicant): This competing continuation SBIR application proposes to complete a regulatory approvals program on a set of next-generation sleep disorder monitoring sensors. Advanced Medical Electronics (AME) completed in June of 2005 a phase II NIMH SBIR developing sleep sensors with embedded wireless links. AME completed on this phase II program the development of a set of ...

DESCRIPTION (provided by applicant): As the population ages, chronic care becomes increasingly important. The contrast to acute care is significant: a physician can often address acute problems with prescriptions and/or procedures, but this is often not the case for chronic problems that persist day after day, hour after hour. Since it is impractical for most people to hire a live-in nurse, those ...