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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Novel Polymeric Trileaflet Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to produce a fully characterized polyurethane heart valve prosthesis that will be ready for clinical evaluation. Existing replacement valves suffer from several shortcomings. Specifically, biological tissue fixation and methods used to mount the tissue to the supporting stent of bioprostheses cause time dependent structural changes ...

    SBIR Phase II 2007 Department of Health and Human Services
  2. BIOACTIVE POLYMER FOR VENTRICULAR ASSIST DEVICES- SBIR TOPIC #37

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  3. Scalable tools for the analysis of chemical compounds using graph-based querying

    SBC: Acelot, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The generation, manipulation, storage and retrieval of chemical structures and subsequent calculation of various properties, often related to their biological activity, have become extremely important for drug discovery. The resulting field of Cheminformatics has blossomed in recent years and has been a hotbed for the application of data mining and database pri ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Manufacturing Research and Development of 2D Electrostrictive Ultrasonic Arrays

    SBC: ACOUSTX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Proposed is the development of manufacturing processes for electrostrictive arrays allowing for real-time ultrasound volumetric imaging. To date, the commercial development of 2D transducer arrays having thousands of array elements has been significantly limited due to manufacturing inefficiencies, transducer element sensitivity; the complexity associated with ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Identifying Cytoprotectants for Photoreceptors and RPE Cells to Treat Dry AMD

    SBC: ACUCELA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the major cause of irreversible loss of vision in the adult population. AMD can be classified into the "dry" form and the "wet" form. The dry form involves apoptotic changes in the photoreceptor cells or the retinal pigment epithelium (RPE) cells underlying the central retina (macula). The dry form can progress to the w ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. In Vitro Assay to Assess Chemical Toxicity in Retinal Primary Cell Cultures

    SBC: ACUCELA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The average person in the U.S. contains detectable levels of more than 100 industrial compounds, pollutants, and chemicals, but predicting the relative risk of this exposure, especially over time, is challenging (US CDC, 2003). Successful development and commercialization of next-generation, low-cost, high-performance technology for predicting compound toxicity ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. High resolution mapping of the cochlear nerve using optical stimulation

    SBC: Aculight Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Neural prosthetic devices are artificial extensions to the body that restore or supplement nervous system function that was lost during disease or injury. Particular success has been realized in the cochlear prostheses development. In contemporary cochlear implants, however, the injected electric current is spread widely along the scala tympani and across turns ...

    STTR Phase II 2007 Department of Health and Human Services
  8. Creating Medicare and Medicaid Research Files to Augment Census Survey Data

    SBC: Acumen, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR proposal to the National Institute on Aging (NIA) requests funding to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen LLC with earlier support from NIA. The purpose of MedRIC is to facilitate the acquisition and linking of administrative data from the Centers for Medicare and Medicaid Service ...

    STTR Phase I 2007 Department of Health and Human Services
  9. Creating Research Files from CMS Data for Integration with Survey Data

    SBC: Acumen, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR proposal to the National Institute on Aging (NIA) requests funding to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen LLC with earlier support from NIA. The purpose of MedRIC is to facilitate the acquisition and linking of administrative data from the Centers for Medicare and Medicaid Service ...

    STTR Phase I 2007 Department of Health and Human Services
  10. The Neurocognitive Profile: A High Efficiency Integrated Brain-Behavior Assay

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alterations in neurocognitive function play a major role in numerous sleeps, neurological and psychiatric disorders and can have a significant impact on quality of life, treatment efficacy, rehabilitation and ability to function at work and in normal daily activities. The methods currently available for neurocognitive investigations including traditional neur ...

    SBIR Phase I 2007 Department of Health and Human Services

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